| 马燕娟,张莉,李玲.药物联合音乐治疗对青少年首发抑郁症的效果及对睡眠质量的影响[J].四川精神卫生杂志,2019,32(1):42-46.,Efficacy of drug therapy combined with music therapy on curative effect and sleep quality of adolescents with first - episode depression[J].SICHUAN MENTAL HEALTH,2019,32(1):42-46 |
| 药物联合音乐治疗对青少年首发抑郁症的效果及对睡眠质量的影响 |
| Efficacy of drug therapy combined with music therapy on curative effect and sleep quality of adolescents with first - episode depression |
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| DOI：10.11886/j.issn.1007-3256.2019.01.008 |
| 中文关键词: 首发抑郁症 药物治疗 音乐治疗 多导睡眠图 |
| 英文关键词:First - episode depression Drug therapy Music therapy Polysomnography |
| 基金项目:乌鲁木齐市科学技术项目（Y141310045) |
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| 【摘要】 目的 观察药物联合音乐治疗对青少年首发抑郁症患者睡眠质量的影响，为青少年首发抑郁症的治疗提供参考。 方法 选取 2016 年 2 月 - 2017 年 6 月乌鲁木齐市第四人民医院收治的符合《中国精神障碍分类与诊断标准（第 3 版）》(CCMD - 3)抑郁症诊断标准的青少年患者 98 例，采用随机数字表法分为观察组和对照组各 49 例。 两组均给予盐酸舍曲林(50 mg/d)和右佐匹克隆(3 mg/d)治疗，观察组在药物治疗基础上联合音乐治疗，两组均连续治疗 1 个月。 于治疗前后对两组进行汉密尔顿焦虑量表(HAMA)、汉密尔顿抑郁量表 24 项版(HAMD - 24) 和匹兹堡睡眠指数量表(PSQI) 评定，并进行多导睡眠监测(PSG)。 结果 治疗后，观察组总有效率高于对照组，差异有统计学意义(93. 88% vs. 79. 59% ,χ2 = 4. 346，P < 0. 05)；观察组 HAMA、HAMD - 24 评分均低于对照组，差异均有统计学意义( P 均 < 0. 01)；观察组 PSQI 各因子评分、PSG各指标测量值均优于对照组，差异均有统计学意义( P 均 < 0. 01)。 结论 药物联合音乐治疗可能有助于降低青少年首发抑郁症患者的焦虑和抑郁程度，改善其睡眠质量。 |
| 英文摘要: |
| Objective To observe the efficacy of drug combined with music therapy on the curative effect and sleep quality of patients with first - episode depression in adolescents, and to provide references for the selection of treatment plan for the patients. Methods From February 2016 to June 2017, a total of 98 adolescent patients who met the diagnostic criteria of Chinese Classification and Diagnostic Criteria of Mental Disease, third edition ( CCMD - 3) were selected from The Fourth People's Hospital of Urumqi. All subjects were divided into the observation group and control group by random number table method, and 49 cases in each group. Both groups were treated with sertraline hydrochloride ( 50 mg /d) and dexzopiclone ( 3 mg /d) , and the observation group received music therapy in addition. Both two groups were treated for 1 month. Hamilton Anxiety Scale ( HAMA) , Hamilton Depression Scale - 24 item ( HAMD - 24) , Pittsburgh Sleep Quality Index ( PSQI) and polysomnography ( PSG) were used to evaluate the two groups before and after treatment. Results After treatment, the total effective rate of the observation group was higher than that of the control group ( 93 . 88% vs. 79. 59% , χ2 = 4. 346, P < 0. 05 ) . After treatment, the HAMA and HAMD - 24 scores of the observation group were lower than those of the control group ( P < 0. 01 ) . All the factors scores of PSQI and the measured values of PSG of the observation group were better than those of the control group ( P < 0. 01 ) . Conclusion The combination of the drug and music therapy may help reduce anxiety and depression in adolescents with first - episode depression and improve their sleep quality. |
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