| 王雪雯,傅一笑,唐金香.双生子研究方法在精神障碍研究中的应用与进展[J].四川精神卫生杂志,2019,32(2):181-184.,Application and progress of twin study method in mental disorders research[J].SICHUAN MENTAL HEALTH,2019,32(2):181-184 |
| 双生子研究方法在精神障碍研究中的应用与进展 |
| Application and progress of twin study method in mental disorders research |
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| DOI：10.11886/j.issn.1007-3256.2019.02.021 |
| 中文关键词: 精神障碍 双生子 同卵双生子 |
| 英文关键词:Mental disorder Twin Monozygotic twin |
| 基金项目:国家自然科学基金资助项目(81101025)；重庆市科委资助项目(cstc2016shmszx130051)；重庆市卫计委资助项目(2016MSXM010)；重庆市教委资助项目(17SKG017)；重庆市科委资助项目(cstc2018jcyjA1420) |
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| 中文摘要: |
| 【摘要】 精神障碍的病因学研究备受关注,目前认为遗传和环境因素对精神障碍的发生发展有重要作用.双生子研究设计是常用于量化遗传和环境影响的研究方法之一,通过双生子来研究精神障碍有着显著的优势。本文分别就双生子的定义、双生子研究的优势和局限性及其在精神障碍研究中的进展进行综述,旨在为深入研究精神障碍发病机制提供参考。 |
| 英文摘要: |
| The etiology of mental disorders had received much attention and it was believed that genetic and environment played an important role in the development of mental disorders. Twin study design was one of the methods commonly used to quantify genetic and environmental impacts, and there were many advantages to study mental disorders through twins. This paper reviewed the context included the definitions of twins, the advantages and limitations of twin study, and the progress of twin research method in the study of mental disorders, which was to reveal the pathogenesis of mental disorders. |
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