| 叶飞英,郭彦杨,王锋锐,刘小聪,钟艳琳,余秋容.住院精神分裂症男性患者吸烟行为与认知功能的关系[J].四川精神卫生杂志,2014,27(1):51-54.YE Fei - ying,GUO Yan - yang,WANG Feng - rui,LIU Xiao - cong,ZHONG Yan- lin,YU Qiu -rong,Association between cognitive functions and smoking behaviors in male patients with schizophrenia[J].SICHUAN MENTAL HEALTH,2014,27(1):51-54 |
| 住院精神分裂症男性患者吸烟行为与认知功能的关系 |
| Association between cognitive functions and smoking behaviors in male patients with schizophrenia |
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| DOI： |
| 中文关键词: 精神分裂症 吸烟 认知功能 横断面研究 |
| 英文关键词:Schizophrenia Smoking Cognitive function Cross - sectional study |
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| 中文摘要: |
| 目的 探索住院精神分裂症男性患者吸烟行为与认知功能的关系.方法 收集2010年3月-2012年4月在惠州二院住院的、符合《国际疾病分类（第10版）》（ICD-10）精神分裂症诊断标准男性患者397例,其中慢性精神分裂症患者315例（吸烟组245例,非吸烟组70例）,首发精神分裂症患者82例（吸烟者28例,非吸烟者54例）,所有受试者都接受吸烟状况调查：尼古丁依赖量表（FIND）,根据FTND分值,把吸烟组分为重度依赖组和轻度依赖组;并接受认知功能检查：连续作业测验（GPT）,威斯康星卡片分类（WCST）和重复性成套神经心理状态测验（RBANS）.结果 在315例慢性精神分裂症患者中,吸烟组245例（77.8％）,非吸烟组70例（22.2％）;在82例首发精神分裂症患者中,吸烟者28例（34.1％）,非吸烟者54例（65.9％）.①慢性男性精神分裂症患者,吸烟组和非吸烟组在CPT、SWCT、RBANS各项评分差异均无统计学意义（P均＞0.05）;重度依赖组CPT的正确反应数大于轻度依赖组和非吸烟组,且差异有统计学意义（P＜0.01）,轻度依赖组和非吸烟组差异无统计学意义（P＞0.c5）.②首发男性精神分裂症患者,吸烟组和非吸烟组在CPT、SWCT、RBANS各项评分差异无统计学意义（P均＞0.05）.结论 吸烟对于精神分裂症患者的持续注意可能有一定的正性作用,吸烟与认知功能存在一定的相关性 |
| 英文摘要: |
| Objective To explore the relationship between smoking behavior in male patients with schizophrenia and cognitive function. Methods Collecting hospitalized patients who lived from March 2010 - April 2012 in Huizhou second hospital, and met ICD - 10 criteria for schizophrenia. There were 397 male patients were collected, of which 315 cases with chronic schizophrenia （smoking group 245 cases, non smoking group 70 cases） , 82 cases of patients with first - episode schizophrenia （ smokers in 28 cases, 54 cases of non smoker）. All subjects received smoking status： Fagerstrom Testfor Nicotine Dependence, FIND, cognitive tests testes（ Gordon continuous performancetest, CFF, Wisconsin Cards Sort WCSTand Repeatable Batteryfor the Assessment of Neuro psychological Status, RBANS）. Results In patients with chronic schizophrenia, patients who smoking were 245 （77.8%） while non - smoking patients were 70 （22.2%）; In 82 cases of first -episode schizophrenic patients, 28 were smokers （34.1%）, while 54 cases were non - smokers （65.9%）. （1）In male patients with chronic schizophrenia, smoking group and non smoking group had no significant difference in CPT, SWCT, RBANS scores （ P 〉 0.05 ）. The number of correct responses of CPT in severe dependence group was significantly greater than that of light dependent group and non smoking group （ P 〈 0.01 ）, and there were no significant difference between light dependent group and non smoking group （ P 〉 0.05 ）. （2）The first male patients with schizophrenia, there were no significant difference between smoking group and non smoking group in CPT, SWCT, RBANS scores （P 〉 0.05 ）. Conclusion Smoking may have a posi- tive effect on sustained attention in schizophrenia, suggesting that smoking may relate to cognitive function |
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