谢侃侃,张景春,赵灿.精神病托管机构抗精神病药物使用情况调查[J].四川精神卫生杂志,2019,32(4):333-336.
精神病托管机构抗精神病药物使用情况调查
Survey of antipsychotic drug use in psychiatric hosting service center
投稿时间:2019-04-10  
DOI:10.11886/j.issn.1007-3256.2019.04.009
中文关键词:  精神病托管机构  非医疗职能机构  抗精神病药  现况调查
英文关键词:Nursing home for mental illness  Non-medical functional institution  Antipsychotics  Cross-sectional survey
基金项目:
作者单位
谢侃侃 北京市朝阳区第三医院 
张景春 北京市朝阳区第三医院 
赵灿 北京市朝阳区第三医院 
摘要点击次数:
全文下载次数:
中文摘要:
      【摘要】 目的 了解北京市朝阳区精神病托管中心抗精神病药物使用情况,为托管机构患者的药物管理提供参考。方法 选取2017年6月在北京市朝阳区精神病托管服务中心住院、符合《国际疾病分类(第10版)》(ICD-10)精神疾病诊断标准并接受抗精神病药物治疗的患者为研究对象,采用自编调查问卷收集患者的社会人口学资料、临床诊断及用药情况。结果 共197例患者纳入研究,其中使用单一抗精神病药物的患者共180例(91.4%),联合使用两种及以上抗精神病药物的患者17例(8.6%)。使用频率最高的抗精神病药物前五位依次是氯丙嗪[54例次(25.0%)]、氯氮平[37例次(17.1%)]、氟哌啶醇[26例次(12.0%)]、利培酮[23例次(10.6%)]和舒必利[22例次(10.2%)]。接受第一代抗精神病药物治疗的患者病程(Z=-3.260,P<0.05)和住院时间更长(Z=-3.531,P<0.01)。Logistc回归分析显示:住院时间是使用第一代抗精神病药物的相关因素(β=0.099,OR=1.104,95% CI=1.033~1.179,P<0.05)。结论 北京市朝阳区精神病托管中心住院患者以使用单一抗精神病药为主,使用第一代抗精神病药物更多,住院时间长的患者倾向于使用第一代抗精神病药物。
英文摘要:
      Objective To explore the antipsychotic drug use of patients in Psychiatric Hosting Service Center of Chaoyang District in Beijing, and to provide references for drug management of patients in the care center.Methods Patients who were hospitalized in Psychiatric Hosting Service Center of Chaoyang District in Beijing in June 2017 and were in accordance with International Classification of Diseases, tenth edition (ICD-10) psychiatric diagnosis were selected as the subjects of this study. All the enrolled patients received antipsychotic drugs while in hospital. Data including social demographic data, diagnosis and drug use of patients were collected by self-made questionnaires.Results A total of 197 patients were enrolled in the study, including 180 (90.5%) patients used single antipsychotic medication and 17 (8.5%) cases used drug combination. And the most frequently used antipsychotics were chlorpromazine (n=54), clozapine (n=37), haloperidol (n=26), risperidone (n=23) and sulpiride (n=22), accounting for 25.0%, 17.1%, 12.0%, 10.6% and 10.2% respectively. Patients receiving the first-generation antipsychotics had a significantly longer course of disease (Z=-3.260, P<0.05) and hospital stay (Z=-3.531, P<0.01). Logistic regression analysis showed that hospital stay was a related factor of using the first-generation antipsychotics (β=0.099, OR=1.104, 95% CI=1.033~1.179, P<0.05).Conclusion In Psychiatric Hosting Service Center of Chaoyang District in Beijing, patients are mainly treated with single antipsychotic medication, and mostly first-generation antipsychotics. For patients with long hospitalization length, the first-generation antipsychotics are the most frequently used.
      附件
查看全文  查看/发表评论  下载PDF阅读器
关闭
手机扫一扫