黄佩佩,吕丽,刘传新.细胞色素P4502E1及其基因多态性与酒精依赖的关系[J].四川精神卫生杂志,2020,33(1):92-96.Huang Peipei,Lyu Li,Liu Chuanxin,Relationship between cytochrome P4502E1 and its gene polymorphismand alcohol dependence[J].SICHUAN MENTAL HEALTH,2020,33(1):92-96
细胞色素P4502E1及其基因多态性与酒精依赖的关系
Relationship between cytochrome P4502E1 and its gene polymorphismand alcohol dependence
投稿时间:2019-12-13  
DOI:10.11886/scjsws20191213002
中文关键词:  细胞色素P4502E1  CYP2E1  基因  酒精依赖  综述
英文关键词:Cytochrome P4502E1  CYP2E1  Gene  Alcohol dependence  Review
基金项目:山东省自然科学基金(项目名称:中国人群中酒精依赖的遗传学研究,项目编号:ZR2016HM55)
作者单位邮编
黄佩佩 济宁医学院精神卫生学院山东 济宁 272067 272067
吕丽 济宁医学院精神卫生学院山东 济宁 272067 272067
刘传新 济宁医学院精神卫生学院山东 济宁 272067 272067
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中文摘要:
      本文通过对细胞色素P4502E1(CYP2E1)及其基因多态性与酒精依赖的关系进行综述,以期为酒精依赖的早期干预提供参考。本文介绍了与酒精依赖相关的CYP2E1基因多态性以及与CYP2E1相关的酒精性疾病,在中国知网、万方、PubMed数据库检索相关文献,总结当前研究可能存在的不足,为后续研究提供参考。
英文摘要:
      The purpose of this paper was to review the relationship between cytochrome P4502E1 (CYP2E1) and its gene polymorphism and alcohol dependence, in order to provide reference for the early intervention of alcohol dependence. This paper introduced the alcohol dependence related CYP2E1 gene polymorphism and the CYP2E1 related alcoholic diseases. Relevant literatures on CNKI, Wanfang and PubMed databases were searched to summarize the possible deficiencies of current studies, so as to provide reference for the follow-up research.
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