| 孙振晓,徐春梅,赵林.奥氮平致呃逆1例[J].四川精神卫生杂志,2021,34(2):180-181.Sun Zhenxiao,Xu Chunmei,Zhao Lin,Olanzapine-induced hiccups： a case report[J].SICHUAN MENTAL HEALTH,2021,34(2):180-181 |
| 奥氮平致呃逆1例 |
| Olanzapine-induced hiccups： a case report |
| 投稿时间：2021-02-23 |
| DOI：10.11886/scjsws20210223001 |
| 中文关键词: 奥氮平 呃逆 不良反应 |
| 英文关键词:Olanzapine Hiccups Adverse reaction |
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| 中文摘要: |
| 本文目的是通过报道1例奥氮平致呃逆，以引起临床医生对此不良反应的关注。1例47岁的男性癫痫性精神障碍患者，既往无重大躯体疾病史及呃逆病史，在接受丙戊酸钠缓释片及卡马西平治疗基础上，加用奥氮平10 mg/d，4天后出现持续性呃逆，停用奥氮平2天后，呃逆消失。再次应用奥氮平7天后又出现持续性呃逆，停用奥氮平2天后，呃逆又消失，期间丙戊酸钠缓释片及卡马西平剂量未变，提示系奥氮平所致呃逆。本案例提示临床上在应用奥氮平时，应考虑到引起呃逆的可能性。 |
| 英文摘要: |
| The case report aims to raise the concern of clinicians about hiccups as an adverse reaction in olanzapine treatment. A 47-year-old male patient with epileptic mental disorder appeared symptoms of persistent hiccups on the fourth day of treatment with sodium valproate and carbamazepine jointing 10 mg/d olanzapine， and the symptoms disappeared two days after olanzapine withdrawal. The patient began to take olanzapine again， hiccups reappeared seven days after administration and relieved two days after withdrawal. During the whole treatment period， the dosage of sodium valproate and carbamazepine remained unchanged， indicating that the hiccups was induced by olanzapine. This case suggests that the possibility of hiccups should be considered in the clinical application of olanzapine. |
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