李海静,佘生林,邝启杰,郑英君,夏雨.首发精神分裂症患者快感缺乏的成分特征与相关因素[J].四川精神卫生杂志,2021,(4):328-331.
首发精神分裂症患者快感缺乏的成分特征与相关因素
Analysis of the component factors and connected factors of anhedonia in patients with first-episode schizophrenia
投稿时间:2021-04-29  
DOI:10.11886/scjsws20210429002
中文关键词:  精神分裂症  快感缺乏  愉快情绪体验量表
英文关键词:Schizophrenia  Anhedonia  Temporal experience of pleasure scale
基金项目:广州市卫生健康科技一般引导项目(项目名称:精神分裂症情绪信息视听整合障碍与社交退缩相关性的神经电生理研究,项目编号:20201A011045);广州市科技计划项目(项目名称:精神分裂症面孔情绪认知障碍的神经机制研究,项目编号:201904010267)
作者单位邮编
李海静 广州医科大学附属脑科医院广东 广州 510370 510370
佘生林 广州医科大学附属脑科医院广东 广州 510370 510370
邝启杰 广州医科大学附属脑科医院广东 广州 510370 510370
郑英君 广州医科大学附属脑科医院广东 广州 510370 510370
夏雨 广州医科大学附属脑科医院广东 广州 510370 510370
摘要点击次数:
全文下载次数:
中文摘要:
      目的 探索首发精神分裂症患者快感缺乏的成分特征及其与临床症状、认知功能和社会功能的相关性。方法 纳入符合《国际疾病分类(第10版)》(ICD-10)诊断标准的31例首发精神分裂症患者和33例健康对照组。使用愉快情绪体验量表(TEPS)、阳性和阴性症状量表(PANSS)、重复性成套神经心理状态测验(RBANS)以及个人和社会功能量表(PSP)对患者的快感缺乏情况、精神症状、认知功能和社会功能进行评定。采用Pearson相关分析测查快感缺乏与临床症状、认知功能和社会功能的相关性。结果 首发精神分裂症患者TEPS消费性快感评分低于健康对照组,差异有统计学意义[(27.71±5.48)分vs.(31.58±5.92)分,t=2.705,P=0.009]。相关分析显示,首发精神分裂症患者消费性快感缺乏与PANSS、RBANS和PSP评分的相关均无统计学意义(P>0.05)。结论 首发精神分裂症患者存在消费性快感缺乏,其消费性快感缺乏可能独立于临床症状、认知功能损害和社会功能损害之外。
英文摘要:
      Objective To explore the component factors of anhedonia in first-episode schizophrenia patients and the relationship with clinical symptoms, cognitive and social functioning.Methods A total of 31 patients with first-episode schizophrenia who met the diagnostic criteria of the International Classification of Diseases, tenth edition (ICD-10) and another 33 healthy controls were enrolled. Then, the anhedonia level, mental symptoms, cognitive and social functioning were assessed using Temporal Experience of Pleasure Scale (TEPS), Positive and Negative Syndrome Scale (PANSS), Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) and Personal and Social Performance Scale (PSP). Thereafter, Pearson correlation was used to discuss the correlation of anhedonia level with clinical symptoms, cognitive and social functioning.Results The consummatory anhedonia score in TEPS of first-episode schizophrenia patients was lower than that of healthy controls, with statistical difference [(27.71±5.48) vs. (31.58±5.92), t=2.705, P=0.009]. Correlation analysis showed that consummatory anhedonia had no correlation with PANSS, RBANS and PSP scores in first-episode schizophrenia patients(P>0.05).Conclusion First-episode schizophrenia patients have consummatory anhedonia, and the consummatory anhedonia may be independent of clinical symptoms, cognitive and social functioning.
查看全文  HTML  查看/发表评论  下载PDF阅读器
关闭