| 邢笑萌,梁思想,刘君,沙莎.MATRICS成套神经认知测试在青少年双相障碍患者中的心理测量学特征[J].四川精神卫生杂志,2022,35(3):223-229.Xing Xiaomeng,Liang Sixiang,Liu Jun,Sha Sha,Psychometric properties of the MATRICS Consensus Cognitive Battery in young patients with bipolar disorder[J].SICHUAN MENTAL HEALTH,2022,35(3):223-229 |
| MATRICS成套神经认知测试在青少年双相障碍患者中的心理测量学特征 |
| Psychometric properties of the MATRICS Consensus Cognitive Battery in young patients with bipolar disorder |
| 投稿时间：2022-02-28 |
| DOI：10.11886/scjsws20220228001 |
| 中文关键词: 双相障碍 MATRICS成套神经认知测试 信度 效度 |
| 英文关键词:Bipolar disorder MATRICS Consensus Cognitive Battery Reliability Validity |
| 基金项目: |
|
| 摘要点击次数: |
| 全文下载次数: |
| 中文摘要: |
| 目的 检测MATRICS成套神经认知测试（MCCB）在青少年双相障碍患者中的心理测量学特征，以确定MCCB是否可用于青少年双相障碍患者的认知功能评估。方法 按照年龄、性别和受教育程度匹配的原则，纳入青少年双相障碍患者（n=38）、青少年重度抑郁发作患者（n=40）和健康对照组（n=41）。分别在基线期和2周后，对青少年双相障碍患者进行蒙特利尔认知评估量表（MoCA）和MCCB评定，其他研究对象仅接受基线期MCCB评定。采用Cronbach’s α系数评估MCCB内部一致性，使用Pearson相关分析考察重测信度与效标效度，通过协方差分析表示区分效度，使用验证性因子分析探讨MCCB的结构效度。结果 ①在对青少年双相障碍患者的评定结果中，MCCB基线期和2周后重测的Cronbach’s α系数分别为0.784、0.773。②青少年双相障碍患者2周后MCCB重测结果显示，MCCB各维度重测信度为0.630~0.812（P均<0.01）。③效标效度显示，MoCA的短期记忆维度评分与MCCB的信息处理速度以及言语学习和记忆维度评分均呈正相关（r=0.487、0.522，P<0.05或0.01）。④区分效度显示，青少年双相障碍组、青少年重度抑郁发作组和健康对照组在MCCB的信息处理速度、注意/警觉性、工作记忆、言语学习和记忆、视觉学习和记忆以及推理与问题解决能力六个维度的评分中，差异均有统计学意义（F=3.790~7.243，P均<0.01）。⑤探索性因子分析显示，MCCB中存在四个因子，累计方差解释率为71.65%。验证性因子分析提示理想7因子模型结构效度欠佳。结论 MCCB在青少年双相障碍患者中具有较好的内部一致性、重测信度以及可接受的效度。 |
| 英文摘要: |
| Objective To investigate the psychometric features of MATRICS Consensus Cognitive Battery （MCCB） in adolescents with bipolar disorder， so as to evaluate its appropriateness for the measurement of cognitive deficits in adolescents with bipolar disorder.Methods Adolescents with bipolar disorder （n=38）， adolescents with major depressive episode （n=40） and healthy controls （n=41） matched on age， sex and educational background were enrolled. Adolescents with bipolar disorder were assessed using Montreal Cognitive Assessment Scale （MoCA） and MCCB at baseline and 2 weeks later， while the rest were only assessed using MCCB at baseline. Thereafter， the psychometric features of MCCB such as internal consistency， test-retest reliability and criterion-related validity， discriminant validity and structural validity were evaluated using Cronbach's α coefficient， Pearson correlation analysis， analysis of covariance and confirmatory factor analysis.Results ①The Cronbach's α coefficient of MCCB in adolescents with bipolar disorder was 0.784 at baseline and 0.773 at two weeks later， respectively. ②Among adolescents with bipolar disorder， the test-retest reliability over a two-week interval of each dimension in MCCB ranged from 0.630 to 0.812 （P<0.01）. ③ The criterion-related validity denoted that the score of short-term memory domain in MoCA was positively correlated with the speed of processing， verbal learning and working memory in MCCB （r=0.487， 0.522， P<0.05 or 0.01）. ④ Discriminant validity analysis implied that the scores of the processing speed， attention/vigilance， working memory， verbal learning and memory， visual learning and memory， reasoning and problem solving in MCCB yielded statistical differences among adolescents with bipolar disorder， adolescents with major depressive episode and healthy controls （F=3.790~7.243， P<0.01）. ⑤ Exploratory factor analysis showed that cumulative total variance contribution rate of MCCB amounted to 71.65% of four factors， and the confirmatory factor analysis indicated that the ideal 7-factor model had poor structural validity.Conclusion MCCB has good internal consistency， retest reliability and acceptable validity in adolescents with bipolar disorder. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |