徐子尧,黄亚玲,朱光强,王旭,王芳.中国青少年抑郁症患者非自杀性自伤行为发生率的Meta分析[J].四川精神卫生杂志,2022,35(4):331-336.Xu Ziyao,Huang Yaling,Zhu Guangqiang,Wang Xu,Wang Fang,Prevalence of non-suicidal self-injury behavior among Chinese adolescents with depression: a Meta-analysis[J].SICHUAN MENTAL HEALTH,2022,35(4):331-336
中国青少年抑郁症患者非自杀性自伤行为发生率的Meta分析
Prevalence of non-suicidal self-injury behavior among Chinese adolescents with depression: a Meta-analysis
投稿时间:2022-04-21  
DOI:10.11886/scjsws20220421002
中文关键词:  青少年  抑郁症  非自杀性自伤  Meta分析
英文关键词:Adolescents  Depression  Non-suicidal self-injury  Meta-analysis
基金项目:
作者单位邮编
徐子尧 成都中医药大学四川 成都 610075 610075
黄亚玲 成都中医药大学四川 成都 610075 610075
朱光强 广汉市人民医院四川 德阳 618300 618300
王旭 成都中医药大学四川 成都 610075 610075
王芳* 成都中医药大学附属医院四川 成都 610075 610075
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中文摘要:
      目的 分析中国青少年抑郁症患者非自杀性自伤(NSSI)行为发生率,为对其NSSI行为进行干预提供参考。方法 计算机检索中国知网、维普、万方、中国生物医学文献数据库、PubMed、Web of Science、Cochrane Library、Embase数据库中关于青少年抑郁症患者NSSI行为发生率的横断面调查研究,检索时限均为建库至2022年2月。由2名研究员筛选文献、提取资料并对文献进行质量评价,采用RevMan 5.4进行Meta分析。结果 最终纳入10篇文献,共2 238例患者。Meta分析结果显示,中国青少年抑郁症患者NSSI行为发生率为51%(95% CI:43%~59%)。亚组分析结果显示,女性青少年抑郁症患者NSSI行为发生率为36%(95% CI:22%~50%),高于男性NSSI行为发生率18%(95% CI:12%~24%);有自杀意念的青少年抑郁症患者NSSI行为发生率为57%(95% CI:38%~77%),高于无自杀意念者NSSI行为发生率4%(95% CI:0~8%);以《精神障碍诊断与统计手册(第5版)》(DSM-5)为诊断标准进行诊断的患者NSSI行为发生率为54%(95% CI:41%~67%),高于以《国际疾病分类(第10版)》(ICD-10)进行诊断的患者NSSI行为发生率46%(95% CI:40%~51%);在方法学质量评价评分为7分的文献中,患者NSSI行为发生率为52%(95% CI:41%~63%),与评分为6分的文献中患者NSSI行为发生率50%(95% CI:44%~55%)接近。以上各亚组比较,差异均有统计学意义(P<0.05或0.01)。结论 中国青少年抑郁症患者NSSI行为发生率较高,且女性高于男性、有自杀意念者高于无自杀意念者。
英文摘要:
      Objective To analyze the prevalence rate of non-suicidal self-injury (NSSI) behavior in Chinese adolescents with depression, so as to provide references for the intervention of NSSI behavior in adolescents with depression.Methods The literature databases such as CNKI, VIP, Wanfang, China Biology Medicine Disc, PubMed, Web of Science, Cochrane Library and Embase were searched via computer for the cross-sectional studies related to the prevalence of NSSI behavior in adolescents with depression published from inception to February, 2020. Then the eligibility assessment, data extraction and assessment of methodological quality were performed independently by two reviewers, and the Meta-analysis was performed by using RevMan 5.4.Results A total of 2 238 adolescents in 10 studies were included. Meta-analysis yielded that the prevalence rate of NSSI behavior in Chinese adolescents with depression was 51% (95% CI: 43%~59%). Subgroup analysis of NSSI behavior in adolescents with depression implied that the prevalence rate was 36% (95% CI: 22%~50%) in female adolescents, which was higher than 18% (95% CI: 12%~24%) in male adolescents. The prevalence rate of NSSI behavior was 57% (95% CI: 38%~77%) in depression adolescents with suicidal ideation, which was higher than 4% (95% CI: 0~8%) in those without suicidal ideation. The prevalence rate of NSSI behavior was 54% (95% CI: 41%~67%) in depression adolescents diagnosed with Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5), which was higher than 46% (95% CI: 40%~51%) in those diagnosed with the International Classification of Diseases, tenth edition (ICD-10). The prevalence rate of NSSI behavior was 52% (95% CI: 41%~63%) in depression adolescents in the literatures with quality score of 7, which was close to 50% (95% CI: 44%~55%) in depression adolescents in the literatures with quality score of 6. The comparison of above subgroups all had statistical differences (P<0.05 or 0.01).Conclusion Chinese adolescents with depression suffer a high prevalence rate of NSSI behavior, with higher prevalence in females than in males, and in those with suicidal ideation than in those without suicidal ideation.
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