| 闫振杰,吴佩芸,戴尊孝.精神分裂症患者静息态脑电微状态特征及研究进展[J].四川精神卫生杂志,2023,36(2):181-185.Yan Zhenjie,Wu Peiyun,Dai Zunxiao,Characteristics and research progress of resting-state EEG microstates in patients with schizophrenia[J].SICHUAN MENTAL HEALTH,2023,36(2):181-185 |
| 精神分裂症患者静息态脑电微状态特征及研究进展 |
| Characteristics and research progress of resting-state EEG microstates in patients with schizophrenia |
| 投稿时间：2022-10-30 |
| DOI：10.11886/scjsws20221030001 |
| 中文关键词: 精神分裂症 静息态 脑电微状态 |
| 英文关键词:Schizophrenia Resting-state EEG Microstate |
| 基金项目:西安市卫生健康委员会面上培育项目（项目名称：有暴力行为精神分裂症患者的人格特质及脑电微观状态研究，项目编号：2020ms16） |
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| 中文摘要: |
| 本文目的是探讨精神分裂症患者静息态脑电微状态的特征和研究进展，以期从神经电生理的角度为精神分裂症的临床研究提供参考。于2022年9月在中国知网、万方数据知识服务平台和PubMed数据库进行计算机检索，最终纳入符合标准的文献共27篇。既往研究结果显示，静息状态下精神分裂症患者总是有着更多的C类脑电微状态和更少的D类脑电微状态，这使得静息态脑电微状态具有成为疾病内表型的潜质。虽然，精神分裂症患者的精神症状与静息态脑电微状态之间的相关性目前仍不明确，但可以肯定的是，治疗前后患者静息态脑电微状态的变化是有意义的。 |
| 英文摘要: |
| The purpose of this article is to identify the characteristics and research progress of resting-state EEG microstates in patients with schizophrenia， in order to provide references for clinical research of schizophrenia from the perspective of neuroelectrophysiology. In September 2022， literature was retrieved from CNKI， Wanfang Data Knowledge Service Platform and PubMed database， and 27 studies meeting the requirements were finally included. Previous studies have demonstrated that patients with schizophrenia show increased presence of microstate class C and decreased presence of microstate class D in resting-state recordings， and the two commonly EEG microstate classes have been suggested as a potential endophenotype for schizophrenia. Although the correlation between psychiatric symptoms and resting-state EEG microstate abnormalities in patients with schizophrenia remains unclear， the altered resting-state EEG microstates in patients before and after treatment have undoubtedly validated its clinical significance. |
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