李亚菊,邓吉宝,王永杰,霍小宁,杨小龙.经颅直流电刺激对精神分裂症患者认知功能改善效果的系统评价[J].四川精神卫生杂志,2024,37(5):482-486.Li Yaju,Deng Jibao,Wang Yongjie,Huo Xiaoning,Yang Xiaolong,Systematic evaluation of the therapeutic effect of transcranial direct current stimulation on cognitive function in patients with schizophrenia[J].SICHUAN MENTAL HEALTH,2024,37(5):482-486
经颅直流电刺激对精神分裂症患者认知功能改善效果的系统评价
Systematic evaluation of the therapeutic effect of transcranial direct current stimulation on cognitive function in patients with schizophrenia
投稿时间:2023-12-10  
DOI:10.11886/scjsws20231210001
中文关键词:  经颅直流电刺激  精神分裂症  认知功能
英文关键词:Transcranial direct current stimulation  Schizophrenia  Cognitive function
基金项目:兰州市卫生健康科技发展项目(项目名称:电针对不同病程精神分裂症患者的工作记忆改善研究,项目编号:2021024)
作者单位邮编
李亚菊 甘肃中医药大学第一临床学院甘肃 兰州 730000 730000
邓吉宝 甘肃中医药大学第一临床学院甘肃 兰州 730000 730000
王永杰 甘肃中医药大学第一临床学院甘肃 兰州 730000
兰州市第三人民医院甘肃 兰州 730050 
730050
霍小宁* 甘肃中医药大学第一临床学院甘肃 兰州 730000
兰州市第三人民医院甘肃 兰州 730050 
730050
杨小龙 兰州市第三人民医院甘肃 兰州 730050 730050
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中文摘要:
      背景 认知功能下降是精神分裂症患者的标志性症状,经颅直流电刺激(tDCS)可改善患者的认知功能。目的 对tDCS改善精神分裂症患者认知功能的效果进行系统评价,为精神分裂症患者认知功能的临床干预提供参考。方法 于2023年9月12日,计算机检索中国知网、万方、维普、PubMed、CINAHL和PsycINFO数据库,系统收集有关tDCS改善精神分裂症患者认知功能的随机对照试验。采用Cochrane偏倚风险评估工具2.0版本(RoB 2.0)对纳入文献的偏倚风险进行评价。结果 共纳入17篇文献,包含953例精神分裂症患者。tDCS对精神分裂症患者的信息处理速度、注意力、工作记忆、执行功能、学习能力等认知功能均有改善作用。结论 tDCS可能对精神分裂症患者的认知功能具有改善作用。
英文摘要:
      Background Decline in cognitive function is considered a hallmark of schizophrenia, and transcranial direct current stimulation (tDCS) has developed as a promising tool for cognitive enhancement.Objective To systematically evaluate the effect of tDCS on improving cognitive functioning in patients with schizophrenia, so as to provide references for clinical intervention of cognitive function in patients with schizophrenia.Methods A computer-based systematic search was conducted on September 12, 2023 through CNKI, Wanfang, VIP, PubMed, CINAHL and PsycINFO databases, and randomized controlled trials relevant to the efficacy of tDCS for management of cognitive function in patients with schizophrenia were collected. The risk of bias was assessed using the Cochrane Risk of Bias Tool for Randomized Trials (RoB 2.0).Results A total of 17 articles were included, including 953 patients with schizophrenia. TDCS has an improvement effect on cognitive functions such as information processing speed, attention, working memory, executive function and learning ability in patients with schizophrenia.Conclusion tDCS may have an effect on improving cognitive deficits in patients with schizophrenia. [Funded by Lanzhou Health Science and Technology Development Project (number, 2021024)]
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