精神分裂症患者内在病耻感与生活质量的关系:自尊和症状严重程度的作用路径
Mediating role of self-esteem and severity of symptoms between internalized stigma and quality of life in patients with schizophrenia Luo Hong, Shao Quan Ming, Liu Yan Ni, Qin Yan Ling, Wang Xian Zhen
投稿时间:2024-07-29  修订日期:2025-03-25
DOI:
中文关键词:  精神分裂症  生活质量  病耻感  自尊  症状和体征
英文关键词:schizophrenia  quality of life  stigma  self-esteem  symptoms and signs
基金项目:湖北省大学生创新创业项目(S202410519027)
作者单位地址
金铭 湖北文理学院 湖北省襄阳市隆中路296号
艾桂局 湖北文理学院 
邵全明 襄阳市安定医院 
刘艳妮 襄阳市安定医院 
王仙珍* 吉林大学中日联谊医院 吉林省长春市仙台大街126号吉林大学中日联谊医院
罗红 湖北文理学院 
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中文摘要:
      目的:探讨精神分裂症患者的内在病耻感与生活质量之间的关系,以及自尊、疾病症状严重程度的中介作用。方法:采用便利抽样法,于2023.4~2023.9采用精神疾病内在病耻感量表、精神分裂症患者生活质量量表、自尊量表、阳性与阴性症状量表对襄阳市、四平市、长春市6所精神卫生中心的309名精神分裂症患者进行问卷调查。结果:精神分裂症患者的内在病耻感、自尊及疾病症状严重程度均可显著预测其生活质量。内在病耻感作用于生活质量的3条中介路径为M1:“内在病耻感→自尊→生活质量”(效应值=-0.144,P<0.01,95%CI [-0.271, -0.042],占总效应的18.8%)、M2:“内在病耻感→症状严重程度→生活质量”(效应值=-0.175,P<0.01,95%CI [-0.286, -0.079],占总效应的22.8%)、M3:“内在病耻感→自尊→症状严重程度→生活质量(效应值=-0.088,P<0.01,95%CI [-0.171,-0.026],占总效应的11.5%)。中介效应占总效应的53.1%,且3条中介效应之间的差异均无统计学意义(P>0.05)。结论:本研究揭示了精神分裂症患者内在病耻感与生活质量的关系及作用路径,临床工作人员应重视患者内在病耻感对生活质量的影响,并通过提升患者的自尊水平及缓解疾病症状严重程度来提高患者的生活质量。
英文摘要:
      Objective: To identify the relationship between internalized stigma and quality of life in patients with schizophrenia, as well as the mediating role of self-esteem and severity of symptoms. Methods: The Internalized Stigma of Mental Illness Scale, Schizophrenia Quality of Life Scale, Self-Esteem Scale, and Positive and Negative Syndrome Scale were used to conduct a questionnaire survey among 309 inpatients with schizophrenia from 6 mental health centers in Xiangyang City, Siping City, and Changchun City from April 2023 to September 2023 by convenient sampling method. Results: The internalized stigma, self-esteem, and severity of symptoms in patients with schizophrenia could significantly effect their quality of life. Internalized stigma influenced quality of life through the following 3 pathways , namely, M1:“internalized stigma→self-esteem→quality of life” (effect value=-0.144, P<0.01, 95% CI [-0.271, -0.042], accounting for 18.8% of the total effect), M2: “internalized stigma→severity of symptoms→quality of life” (effect value=-0.175, P<0.01, 95%CI [-0.286, -0.079], accounting for 22.8% of the total effect], M3: “internalized stigma→self-esteem→severity of symptoms→quality of life”(effect value=-0.088, P<0.01, 95% CI [-0.171,-0.026], accounting for 11.5% of the total effect). The mediating effect accounts for 53.1% of the total effect, and there is no statistically significant difference among M1, M2, and M3 (P>0.05). Conclusion: The study revealed the relationship and mechanism between internalized stigma and quality of life in patients with schizophrenia. To improve their quality of life, mental health personnels should pay attention to the impact of patients’ internalized stigma on their quality of life, focus on improving their self-esteem and alleviating the severity of symptoms.
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