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| 主客观睡眠时间短与慢性失眠障碍患者血脂异常的相关性 |
| Analysis of the Relationship of Dyslipidemia with Subjective and Objective Sleep Duration in Chronic Insomnia Patients |
| 投稿时间：2025-03-04 修订日期：2025-06-05 |
| DOI： |
| 中文关键词: 主观睡眠时间 客观睡眠时间 血脂异常 慢性失眠 |
| 英文关键词:subjective sleep duration, objective sleep duration, dyslipidemia, chronic insomnia |
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| 中文摘要: |
| 背景 慢性失眠障碍已成为当前社会的一种常见疾病，其可能与血脂异常的发生相关，既往针对慢性失眠障碍患者的血脂异常研究多集中于探讨主观睡眠时间与血脂异常的关系；针对客观睡眠时间不足与血脂异常关系的研究有限。
目的 基于主观睡眠时间，探讨慢性失眠障碍患者客观睡眠时间不足与血脂异常之间的关系。
方法 回顾性收集2022年8月—2023年11月在绵阳市第三人民医院住院且符合睡眠障碍国际分类第三版（International Classification of Sleep Disorders，ICSD-3）中慢性失眠障碍诊断标准的患者103例为研究对象。收集患者入院时基本资料、通过多导睡眠监测得出的客观睡眠时间及自我睡眠报告的主观睡眠时间。根据血脂异常定义，将患者分为血脂正常组（n=44）和血脂异常组（n=59），比较其基本资料是否有统计学意义。根据客观睡眠时间将其分为客观睡眠时间≥7 h组（n=71）和客观睡眠时间<7 h组（n=32）、根据主观睡眠时间将其分为主观睡眠时间≥7 h组（n=59）和主观睡眠时间<7 h组（n=44）；通过二元Logistic回归分析分析主客观睡眠时间与血脂异常及其各参数异常之间的关系。
结果 通过主客观睡眠时间对患者进行分组并控制协变量后，相比于客观睡眠时间≥7 h，客观睡眠时间<7 h导致血脂异常的风险高出3.128倍（OR：3.128，95% CI：1.139-8.588）；而主观性睡眠短与血脂异常风险增加无显著相关性。
结论 慢性失眠患者中具有较高的血脂异常率，客观睡眠时间短与血脂异常的风险增高密切相关，而主观睡眠时间短与血脂异常的风险增高并未出现显著的相关性。 |
| 英文摘要: |
| Background Chronic insomnia has become a common condition in society, which may be related to the occurrence of dyslipidemia. Previous studies on dyslipidemia in chronic insomnia patients have mostly focused on exploring the relationship between subjective sleep duration and dyslipidemia; there is limited research on the relationship between objective sleep duration and dyslipidemia.
Objective Based on subjective sleep duration, this study investigates the relationship of dyslipidemia with objective sleep duration in chronic insomnia patients.
Methods A retrospective collection of 103 patients who were hospitalized at the Third Hospital of Mianyang from August 2022 to November 2023 and met the chronic insomnia diagnostic criteria in the ICSD-3 was conducted for the study. General information about the patients at the time of admission was collected, along with objective sleep time obtained through polysomnography and subjective sleep time reported by the patients. Based on the definition of dyslipidemia, the patients were divided into a normal lipid group (n=44) and an abnormal lipid group (n=59), and the general information was compared for statistical significance. Subsequently, based on objective sleep time, the patients were divided into an objective sleep time≥7 h group (n=71) and an objective sleep time<7 h group (n=32); based on subjective sleep time, they were divided into a subjective sleep time≥7 h group (n=59) and a subjective sleep time<7 h group (n=44). A binary logistic regression analysis was performed to examine the relationship between subjective and objective sleep times and dyslipidemia and its various parameters.
Results Dyslipidemia was detected in 57% patients. Grouping by objective and subjective sleep duration and controlling for covariates, results showed objective sleep duration<7 h had a 3.128-fold higher dyslipidemia risk than objective sleep duration≥7 h (OR: 3.128, 95% CI: 1.139~8.588); short subjective sleep duration was not linked with dyslipidemia.
Conclusion Dyslipidemia incidence was high in chronic insomnia individuals. Short objective sleep duration, but not short subjective sleep duration, was linked to higher dyslipidemia risks. |
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