住院双相障碍与精神分裂症患者自知力水平保护性因素分析
Probing protective factors of insight of inpatients of bipolar disorder or schizophrenia
投稿时间:2020-05-22  修订日期:2020-08-10
DOI:
中文关键词:  精神分裂症 双相障碍 自知力 睡眠 运动
英文关键词:Schizophrenia Bipolar disorder Insight Sleep Exercise
基金项目:广东省医学科学技术研究基金(C2018026)
作者单位地址
苏敬华 广州医科大学附属脑科医院,广州市惠爱医院 广州市荔湾区芳村明心路36号
范誉 广州医科大学附属脑科医院,广州市惠爱医院 
谭文艳 广东省精神卫生中心 
陈夕圆 广州医科大学附属脑科医院,广州市惠爱医院 
杨宁 广州医科大学附属脑科医院,广州市惠爱医院 
陈晓东* 广州医科大学附属脑科医院,广州市惠爱医院 广州市荔湾区芳村明心路36号
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中文摘要:
      目的 探讨住院双相障碍及精神分裂症患者自知力水平及其保护性因素。方法 在广州市4家精神科住院部连续入组符合《国际疾病分类(第10版)》(ICD-10)双相障碍或精神分裂症诊断标准的住院患者465例。采用自编人口学及临床特征问卷、治疗态度问卷(ITAQ)分别评定患者的临床特征和自知力水平。通过t检验及卡方检验分析不同自知力水平患者间的人口学、临床特征差异。采用两分类Logistic回归分析探讨自知力的保护因素。结果 年龄小(OR=0.977)、男性(OR=1.705)、曾经结婚或同居(OR=1.677)、诊断为双相障碍(OR=2.185)、最近一个月有悲观厌世(OR=2.663)、每天睡眠时间大于7小时(OR=1.620)、每周运动1~2次(OR=1.770)是住院双相障碍和精神分裂症患者自知力好的保护因素。结论 住院双相障碍和精神分裂症患者自知力差异和多种人口学特征及临床特征相关。
英文摘要:
      Objective To investigate the level of insight and its protective factors in hospitalized patients with bipolar disorder or schizophrenia. Methods Four hundred sixty-five patients who fulfilled the criteria of bipolar disorder or schizophrenia (based on ICD10) were enrolled from four hospitals with psychiatric inpatient department in Guangzhou. A self-designed questionnaire was used to collect demographic and clinical features; Insight and treatment attitude questionnaire (ITAQ), was used to evaluate the level of insight. We used t test and Chi square test to compare demographic and clinical differences between patients with different insight levels. Binary logistic regression analysis was performed to probe the protective factors of insight. Results Being young (OR=0.977), being male (OR=1.705), having been married (OR=1.677), being diagnosed with bipolar disorder (OR=2.185), being pessimistic in the last month (OR=2.663), sleeping more than 7 hours a day (OR=1.620), and exercising 1-2 times a week (OR=1.770) were protective factors of insight for inpatients of bipolar disorder or schizophrenia. Conclusion The insight of bipolar disorder or schizophrenia inpatients is associated with a variety of demographic and clinical features.
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