精神分裂症和强迫症的结构和功能磁共振成像比较研究进展
Progress in comparative study of structural and functional magnetic resonance imaging of schizophrenia and obsessive-compulsive disorder
投稿时间:2021-01-29  修订日期:2021-05-27
DOI:
中文关键词:  精神分裂症 强迫症 结构磁共振 功能磁共振 脑网络
英文关键词:Schizophrenia,Obsessive-compulsive disorder,structural MRI,functional MRI,brain network
基金项目:国家自然科学基金(81871081);无锡市 “双百”中青年医疗卫生拔尖人才资助
作者单位地址
郁晓曼 无锡市精神卫生中心 江苏省无锡市滨湖区荣巷街道156号无锡市精神卫生中心
周振和 无锡市精神卫生中心 
汪帅 无锡市精神卫生中心 
田霖* 无锡市精神卫生中心 江苏省无锡市滨湖区156号无锡市精神卫生中心
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中文摘要:
      【摘要】 精神分裂症和强迫症是常见的两种不同类型的精神疾病,但它们有诸多相似的人口统计学特征和临床特征,并且在病理生理学水平上密切相关。临床上精神分裂症和强迫症的共病率较高,研究提示二者可能有共同的病因学基础,目前它们之间的神经生物学底物和病因学关系仍未明确。现通过对精神分裂症和强迫症的结构和功能磁共振成像的比较研究进展进行综述,有利于探索两种疾病相同和特异的生物学标志物,增进对这两种疾病神经机制的理解。
英文摘要:
      【Abstract】 Schizophrenia and obsessive-compulsive disorder are two different types of common psychiatric disorder diseases,but they have many similar demographic characteristics and clinical features, and are closely related at the level of pathophysiology. The co-morbidity of schizophrenia and obsessive-compulsive disorder is relatively high in clinical, and the studies suggests that they may have a common etiological basis. At present, the neurobiological substrates and etiological relationship between the two diseases is still unclear. By reviewing the progress in comparative study of structural and functional magnetic resonance imaging of schizophrenia and obsessive-compulsive disorder, it is helpful to explore the same and specific biological markers of the two diseases and improve the understanding of the neural mechanisms of the two diseases.
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