| 梁秋凤,梁鸿伟,洪家坤,刘小兵.丙戊酸镁缓释片致全血细胞减少1例[J].四川精神卫生杂志,2019,32(6):562-563.Liang Qiufeng,Liang Hongwei,Hong Jiakun,Liu Xiaobing,Magnesium valproate sustained release tablets induced pancytopenia: a case report[J].SICHUAN MENTAL HEALTH,2019,32(6):562-563 |
| 丙戊酸镁缓释片致全血细胞减少1例 |
| Magnesium valproate sustained release tablets induced pancytopenia: a case report |
| 投稿时间：2019-05-25 |
| DOI：10.11886/scjsws20190525002 |
| 中文关键词: 丙戊酸镁缓释片 全血细胞减少 |
| 英文关键词:Magnesium valproate Pancytopenia |
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| 中文摘要: |
| 丙戊酸镁对各型癫痫的治疗效果较好，同时也是美国食品药品监督管理局（FDA）批准用于治疗双相情感障碍的药物。丙戊酸盐的临床反应个体差异较大，消化道功能紊乱和肝功能异常是丙戊酸镁缓释片常见不良反应，而丙戊酸镁引起全血细胞减少鲜有报道。本案例报道了一例丙戊酸镁缓释片致全血细胞减少，以供临床参考。 |
| 英文摘要: |
| Magnesium valproate has been shown to be clinically effective in the treatment of various types of epilepsy and is an FDA approved drug for bipolar disorder.Clinical reactions of valproate varied greatly among individuals. Digestive tract dysfunction and liver dysfunction were common adverse reactions of magnesium valproate sustained release tablets, while pancytopenia caused by valproate was rarely reported. This paper reported a case of pancytopenia induced by magnesium valproate sustained release tablet, which arouse widespread attention in clinical. |
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