| 姜骁,况伟宏.系统性红斑狼疮共病焦虑抑郁影响因素研究进展[J].四川精神卫生杂志,2023,36(4):380-384.Jiang Xiao,Kuang Weihong,Research progress on the influencing factors of comorbid anxiety and depression in systemic lupus erythematosus[J].SICHUAN MENTAL HEALTH,2023,36(4):380-384 |
| 系统性红斑狼疮共病焦虑抑郁影响因素研究进展 |
| Research progress on the influencing factors of comorbid anxiety and depression in systemic lupus erythematosus |
| 投稿时间：2023-05-15 |
| DOI：10.11886/scjsws20230515002 |
| 中文关键词: 系统性红斑狼疮 焦虑 抑郁 影响因素 |
| 英文关键词:Systemic lupus erythematosus Anxiety Depression Influencing factors |
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| 中文摘要: |
| 系统性红斑狼疮（SLE）是一种自身免疫介导的、全身多组织和器官受累的疾病，SLE与焦虑抑郁共病率高，严重影响患者的疾病转归，给临床诊治带来严重挑战。本文通过对SLE共病焦虑抑郁的影响因素进行综述，以期为优化SLE共病焦虑抑郁的治疗提供参考。本文共纳入25篇原始研究，系统分析了影响SLE共病焦虑抑郁的遗传因素、免疫因素、中枢神经系统因素以及社会心理因素。 |
| 英文摘要: |
| Systemic lupus erythematosus （SLE） is an autoimmune disease in which the immune system mistakenly attacks multiple tissues and organs of the body. The comorbid anxiety and depression are highly prevalent conditions among SLE， thereby worsening the prognosis of patients and posing a serious diagnostic challenge to the clinicians. The purpose of this article is to review the literature available for the influencing factors of comorbid anxiety and depression in SLE， and to provide references for optimizing treatment strategies for SLE patients with comorbid anxiety and depression. A total of 25 original research articles are included to provide a systematic and quantitative review， in which the genetic， immune， central nervous system and socio-psychological factors affecting the comorbid anxiety and depression in SLE are explored. |
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