| [Abstract]Objective: To explore the difference of cognitive impairment between bipolar affective disorder and bipolar affective disorder comorbid borderline personality disorder (BPD) patients. Methods: 60 patients with bipolar affective disorder comorbidity BPD who were treated in the First Hospital of Hebei Medical University from April 2021 to April 2022 were selected as the observation group, including 33 patients with bipolar depression comorbidity BPD and 27 patients with bipolar mania comorbidity BPD. At the same time, 60 patients with bipolar disorder were randomly selected as the control group, including 35 patients with bipolar depression and 25 patients with bipolar mania. The cognitive function was evaluated with the Chinese version of the repeatable battery for the assessment of neuropsychological status (RBANS) and Stroop Color Word Test. Results: In the RBANS evaluation of the observation group, the scores of immediate memory, visual span, speech function and test were (62.33 ± 11.22), (66.72 ± 8.40), (77.28 ± 9.97) and (67.28 ± 9.94), respectively, which were lower than those of the control group, the difference was statistically significant (P<0.05). In Stroop color word test, the time of single word, monochrome, double word and double color in the observation group were (15.10 ± 2.28) s, (20.10 ± 3.11) s, (16.76 ± 2.08) s and (36.61 ± 7.22) s, respectively, which were higher than those in the control group, the difference was statistically significant (P<0.05). There were significant differences in patients with bipolar depression between the observation group and the control group in immediate memory, visual span, speech function and total scores of RBANS assessment, and single word time, monochrome time, double word time and double color time in Stroop color word test (P<0.05). There were statistically significant differences in bipolar mania patients between the observation group and the control group in the speech function and the total score of the RBANS assessment, and in the Stroop color word test in single word time, monochrome time, double word time and double color time (P<0.05). There was no significant difference in RBANS evaluation and Stroop color word test between bipolar depression and bipolar mania patients in the observation group (P>0.05). Conclusion: Compare with patients with bipolar affective disorder, patients with bipolar affective disorder comorbid BPD have more impaired cognitive function. |