彭代辉.抑郁症的临床挑战与研究策略[J].四川精神卫生杂志,2023,(5):385-387.Peng Daihui,Challenges and strategies in depression research[J].SICHUAN MENTAL HEALTH,2023,(5):385-387
抑郁症的临床挑战与研究策略
Challenges and strategies in depression research
投稿时间:2023-10-08  
DOI:10.11886/scjsws20231008003
中文关键词:  抑郁症  临床症状  亚型  生物标志物  科学问题  研究策略
英文关键词:Depression  Clinical symptom  Subtype  Biomarker  Scientific problem  Research strategy
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彭代辉 上海交通大学医学院附属精神卫生中心上海 200030 200030
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中文摘要:
      抑郁症是最常见的精神障碍之一,发病率较高,居全球疾病总负担首位。抑郁症受多种因素交互影响,但目前缺乏抑郁症诊断的生物标志物,也缺乏抑郁症临床亚型的分类标准。本文就抑郁症在脑影像学、神经免疫科学、脑电等方面的研究现状以及相关研究面对的挑战进行探讨,为未来抑郁症的研究方向及策略提供思路。
英文摘要:
      Depression constitutes the most common mental disorder with high prevalence rate, and is the leading contributor to the global burden of disease. Many factors are found to influence the development of depression, whereas either reliable biomarkers for the early diagnosis or diagnostic criteria for subtype classification currently exist for depression. Therefore, this paper gives a detailed discussion on the current status and existing challenges of depression research in the context of brain imaging, psychoneuroimmunology and electroencephalography, thus providing a new perspective for research directions and future strategies related to depression.
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