| 吕龙琴,穆敬平,廖恒,刘丽珠,王熙.团体认知行为治疗对广泛性焦虑障碍的临床疗效及其对患者执行功能的影响[J].四川精神卫生杂志,2024,37(1):21-25.Lyu Longqin,Mu Jingping,Liao Heng,Liu Lizhu,Wang Xi,Effects of group cognitive behavioral therapy on clinical efficacy and executive function in patients with generalized anxiety disorder[J].SICHUAN MENTAL HEALTH,2024,37(1):21-25 |
| 团体认知行为治疗对广泛性焦虑障碍的临床疗效及其对患者执行功能的影响 |
| Effects of group cognitive behavioral therapy on clinical efficacy and executive function in patients with generalized anxiety disorder |
| 投稿时间：2023-06-14 |
| DOI：10.11886/scjsws20230614001 |
| 中文关键词: 团体认知行为治疗 广泛性焦虑障碍 执行功能 |
| 英文关键词:Group cognitive behavioral therapy Generalized anxiety disorder Executive function |
| 基金项目:十堰市科技局引导性科研项目（项目名称：团体认知行为治疗广泛性焦虑障碍的临床研究，项目编号：21Y21） |
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| 中文摘要: |
| 背景 广泛性焦虑障碍（GAD）患者常存在执行功能损害。团体认知行为治疗（CBT）有助于改善GAD患者的负性情绪，但对执行功能的改善效果尚不明确。目的 探讨团体CBT对GAD患者焦虑症状和执行功能的影响，以期为GAD患者的康复治疗提供参考。方法 连续选取2021年3月—2022年8月在十堰市太和医院睡眠心身医学中心住院的、符合《精神障碍诊断与统计手册（第5版）》（DSM-5）中GAD诊断标准的80例患者为研究对象，采用随机数字表法分为研究组（n=40）和对照组（n=40）。两组均接受药物治疗及疾病健康教育，研究组在此基础上接受为期6周、每周1次、每次60~90 min的团体CBT。分别于治疗前和治疗6周后使用汉密尔顿焦虑量表（HAMA）评定焦虑症状，使用额叶功能评定量表（FAB）评定执行功能。结果 重复测量方差分析结果显示，两组HAMA评分的时间效应有统计学意义（F=1 870.320，P<0.01），组间效应以及时间与组间的交互效应无统计学意义（F=1.254、0.293，P均>0.05）。两组FAB评分的时间效应、组间效应以及时间与组间的交互效应均有统计学意义（F=311.190、4.399、7.021，P<0.05或0.01）。进一步分析结果显示，治疗后，两组FAB评分均高于治疗前（t=200.569、115.401，P均<0.01），且研究组FBA评分高于对照组（t=-3.211，P<0.01）。结论 团体CBT联合药物治疗可能有助于降低GAD患者焦虑水平，改善其执行功能。 |
| 英文摘要: |
| Background Previous studies have found that patients with generalized anxiety disorder （GAD） have impaired performance in executive function， and group cognitive behavioral therapy （CBT） has been shown to be effective in alleviating negative affect in patients with GAD， while its efficacy on executive function remains unclear.Objective To explore the efficacy of group CBT on anxiety symptom and executive function in GAD patients， so as to provide references for the rehabilitation program for GAD.Methods A total of 80 consecutive patients with GAD who were hospitalized in Sleep and Psychosomatic Medical Center of Shiyan Taihe Hospital from March 2021 to August 2022 and met the Diagnostic and Statistical Manual of Mental Disorders， fifth edition （DSM-5） diagnostic criteria for GAD were enrolled， and they were assigned into study group （n=40） and control group （n=40） using random number table methods. All patients were subjected to routine medication treatment and regular health education， based on this， study group received group CBT once a week （6 weeks， 60 to 90 minutes per session）. At the enrollment and after 6 weeks of treatment， patients were assessed using Hamilton Anxiety Scale （HAMA） and Frontal Assessment Battery （FAB）.Results ANOVA with repeated measures on HAMA score revealed a significant time effect （F=1 870.320， P<0.01）， no significant group effect and no significant time×group interaction effect （F=1.254， 0.293， P>0.05）. Significant time effect， group effect and time×group interaction effect were reported on FAB scores （F=311.190， 4.399， 7.021， P<0.05 or 0.01）. Further analysis indicated that FAB scores of both groups after treatment were higher than those at baseline （t=200.569， 115.401， P<0.01）.And the FAB score of study group was higher than that of control group after treatment （t=-3.211， P<0.01）.Conclusion Group CBT combined with medication treatment for GAD may alleviate the anxiety symptoms and improve executive function in GAD patients. ［Funded by Shiyan Science and Technology Bureau Pilot Scientific Research Project （number， 21Y21）］ |
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