盐酸度洛西汀治疗抑郁症引发的烦渴多饮1例.
A case report of polydipsia induced by duloxetine hydrochloride in the treatment of depression
投稿时间:2024-02-29  修订日期:2024-05-27
DOI:
中文关键词:  盐酸度洛西汀  抑郁症  抗利尿激素紊乱综合征
英文关键词:Duloxetine hydrochloride  depression  SIADH
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作者单位地址
杨舒婷 兰州大学第一临床医学院 甘肃省.兰州市城关区东岗东路199号
范阿娇* 兰州大学第二医院 甘肃省兰州市城关区翠英门82号
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中文摘要:
      【】盐酸度洛西汀是常用的抗抑郁药之一,其主要作用机制是抑制5-羟色胺与去甲肾上腺素再摄取,提高突触间隙单胺类神经递质的浓度,进而发挥抗抑郁作用,临床广泛应用于抑郁发作的治疗。其副作用除了胃肠道反应、血压升高等之外,偶有引起抗利尿激素分泌紊乱综合征(SIADH)的发生,容易造成漏诊和误诊。本文报道1例盐酸度洛西汀治疗抑郁症引发的烦渴多饮病例,以提高临床医师对该药物引起这一少见不良反应的早期识别。
英文摘要:
      【】 Duloxetine hydrochloride is one of the commonly used antidepressants, its main mechanism of action is to inhibit the reuptake of serotonin and norepinephrine, increase the concentration of monoamine neurotransmitters in the synaptic space, and then play an antidepressant role, which is widely used in the clinical treatment of depression. In addition to gastrointestinal reactions and elevated blood pressure, the side effects occasionally cause the occurrence of anti-diuretic hormone secretion disorder syndrome (SIADH), which is easy to cause missed diagnosis and misdiagnosis. This paper reports a case of duloxetine hydrochloride in the treatment of polydipsia caused by depression, in order to improve the early recognition of this rare adverse reaction caused by duloxetine hydrochloride.
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