| 姜文静,汪旭回,徐之涵,张雪迪,王钟琪,周萍,柳娜.强迫性障碍患者伴发强迫型人格障碍的临床特征和影响因素[J].四川精神卫生杂志,2024,37(4):317-322.Jiang Wenjing,Wang Xuhui,Xu Zhihan,Zhang Xuedi,Wang Zhongqi,Zhou Ping,Liu Na,Clinical features of and influencing factors of obsessive-compulsive personality disorder in patients with obsessive-compulsive disorder[J].SICHUAN MENTAL HEALTH,2024,37(4):317-322 |
| 强迫性障碍患者伴发强迫型人格障碍的临床特征和影响因素 |
| Clinical features of and influencing factors of obsessive-compulsive personality disorder in patients with obsessive-compulsive disorder |
| 投稿时间：2024-03-02 |
| DOI：10.11886/scjsws20240302001 |
| 中文关键词: 强迫型人格障碍 强迫性障碍 临床特征 影响因素 |
| 英文关键词:Obsessive-compulsive personality disorder Obsessive-compulsive disorder Clinical features Influencing factors |
| 基金项目:江苏省科技项目（项目名称：全国多中心强迫症诊疗现况调查及优化认知行为治疗的疗效与神经机制研究，项目编号：BE2021616；项目名称：强迫症电子化专病队列管理及数字化心理干预模式探索，项目编号：BE2022678）；南京市医学科技发展重点项目（项目名称：强迫症及其一级亲属错误处理的分子神经机制研究，项目编号：ZKX20029） |
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| 中文摘要: |
| 背景 强迫型人格障碍和强迫性障碍（OCD）是常见的心理疾病，其临床症状相似，但二者之间的区别有待进一步明确。目的 探讨OCD患者伴发强迫型人格障碍的临床特征和影响因素，为进一步临床诊疗提供参考。方法 选取2022年7月—2023年12月在南京医科大学附属脑科医院门诊和住院治疗的、符合《国际疾病分类（第10版）》（ICD-10）强迫性障碍诊断标准的195例OCD患者为研究对象。采用耶鲁布朗强迫症状分类量表（Y-BOCS）、人格诊断问卷（第四版）（PDQ-4+）、强迫症状分类量表修订版（OCI-R）、贝克抑郁量表（BDI）、贝克焦虑量表（BAI）以及席汉残疾量表（SDS）进行评定。根据PDQ-4+中的强迫型人格障碍分量表评分，将患者分为伴强迫型人格障碍组（n=58）和不伴强迫型人格障碍组（n=137）。采用Pearson相关分析和Spearman相关分析考查患者临床特征与强迫型人格障碍分量表评分之间的相关性。采用多元线性回归分析探讨OCD患者伴发强迫型人格障碍的影响因素。结果 伴和不伴强迫型人格障碍的OCD患者的年龄、精神疾病家族史、未治疗时间、OCI-R囤积维度评分、排序维度评分、总评分、PDQ-4+中的强迫型人格障碍分量表评分、BDI评分比较，差异均有统计学意义（P均≤0.05）。伴强迫型人格障碍的OCD患者未治疗时间、OCI-R总评分、囤积维度评分、排序维度评分和BDI评分与强迫型人格障碍分量表评分均呈正相关（r=0.120、0.526、0.364、0.492、0.414，P均<0.05）。多元线性回归分析结果显示，未治疗时间（β=0.132、P<0.05）、OCI-R囤积维度评分（β=0.283、P<0.05）、排序维度评分（β=0.418、P<0.05）是OCD患者伴发强迫型人格障碍的影响因素。结论 伴强迫型人格障碍的OCD患者未治疗时间可能更长，在囤积和排序方面的功能障碍可能更明显，抑郁症状可能更严重。未治疗时间、囤积症状和排序症状可能是OCD患者伴发强迫型人格障碍的影响因素。 |
| 英文摘要: |
| Background Obsessive-compulsive personality disorder and obsessive-compulsive disorder （OCD） are common psychological disorders with similar clinical symptoms， but the differences between the two need further clarification.Objective To explore the clinical features of and influencing factors of obsessive-compulsive personality disorder in patients with OCD， so as to provide references for further relevant clinical diagnosis and treatment.Methods A total of 195 patients with OCD were selected as the research subjects， who received treatment at the outpatient and inpatient departments of the Affiliated Brain Hospital of Nanjing Medical University from July 2022 to December 2023 and met the diagnostic criteria for OCD in the International Classification of Diseases， tenth edition （ICD-10）. Evaluation was conducted by using the Yale-Brown Obsessive Compulsive Scale （Y-BOCS）， Personality Diagnostic Questionnaire-4+ （PDQ-4+）， Obsessive-Compulsive Inventory-Revised （OCI-R）， Beck Depression Inventory （BDI）， Beck Anxiety Inventory （BAI） and Sheehan Disability Scale （SDS）. In accordance with the score of Obsessive-Compulsive Personality Disorder Scale in PDQ-4+， patients were divided into the OCD group with obsessive-compulsive personality disorder （n=58） and the OCD group without obsessive-compulsive personality disorder （n=137）. Pearson correlation analysis and Spearman correlation analysis were adopted to examine the correlation between clinical features and the score of the Obsessive-Compulsive Personality Disorder Scale. Multiple linear regression analysis was used to explore the influencing factors of OCD patients with obsessive-compulsive personality disorder.Results Statistically significant differences were observed between OCD patients with and without obsessive-compulsive personality disorder in the age， family history of mental illness， time without treatment， hoarding and ranking dimension scores in OCI-R， OCI-R total score， score of Obsessive-Compulsive Personality Disorder Scale in PDQ-4， and BDI score （P≤0.05）. OCD patients with obsessive-compulsive personality disorder in the time without treatment， OCI-R total score， hoarding and ranking dimension scores in OCI-R and BDI score are all positively correlated with the score of the Obsessive-Compulsive Personality Disorder Scale （r=0.120， 0.526， 0.364， 0.492， 0.414， P<0.05）. The results of multiple linear regression analysis showed that time without treatment （β=0.132， P<0.05）， hoarding dimension score （β=0.283， P<0.05） and ranking dimension score in OCI-R （β=0.418， P<0.05） were the influencing factors of OCD patients with obsessive-compulsive personality disorder.Conclusion OCD patients with obsessive-compulsive personality disorder may have longer untreated periods， more pronounced functional impairments in hoarding and sorting and more severe depressive symptoms. Untreated time， hoarding symptoms and sorting symptoms may be influencing factors for OCD patients with obsessive-compulsive personality disorder. ［Funded by Jiangsu Province Science and Technology Project （number， BE2021616；number， BE2022678）； Key Project of Nanjing Medical Science and Technology Development Fund （number， ZKX20029）］ |
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