| 陈敏,吕东升,王峥,侯友.目标特征对抑郁障碍患者前瞻记忆的影响[J].四川精神卫生杂志,2025,38(1):14-21.Chen Min,Lyu Dongsheng,Wang Zheng,Hou You,Effect of target characteristics on prospective memory in patients with depressive disorder[J].SICHUAN MENTAL HEALTH,2025,38(1):14-21 |
| 目标特征对抑郁障碍患者前瞻记忆的影响 |
| Effect of target characteristics on prospective memory in patients with depressive disorder |
| 投稿时间：2024-03-03 |
| DOI：10.11886/scjsws20240303001 |
| 中文关键词: 抑郁障碍 前瞻记忆 目标情绪效价 目标凸显性 |
| 英文关键词:Depressive disorder Prospective memory Target emotional valence Target salience |
| 基金项目:内蒙古自治区卫生健康委医疗卫生科技计划项目（项目名称：抑郁障碍患者认知功能损害与睡眠紊乱关系的研究，项目编号：202202104） |
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| 中文摘要: |
| 背景 抑郁障碍患者的前瞻记忆受损，前瞻记忆的改善有助于抑郁障碍患者回归社会。目前关于抑郁障碍患者前瞻记忆影响因素的研究结果不一致。目的 探讨目标特征（情绪效价和凸显性）对抑郁障碍患者前瞻记忆的影响，为抑郁障碍患者前瞻记忆功能的训练和恢复提供参考。方法 纳入2022年1月—12月在内蒙古自治区精神卫生中心门诊就诊的抑郁障碍患者（n=53），同期在社区招募健康被试作为对照组（n=45）。采用2（被试类型：抑郁组、对照组）×2（目标凸显性：凸显、非凸显）×3（情绪效价：正性、中性、负性）三因素混合实验设计，选择中国情绪图片库（CAPS）中正性、中性、负性三种情绪效价的图片作为实验材料，采用双任务实验范式，记录被试不同目标特征前瞻记忆任务和进行中任务的反应时和正确率。结果 ①在前瞻记忆任务中，被试类型主效应有统计学意义，抑郁组正确率低于对照组（F=14.892，P<0.01），反应时长于对照组（F=10.642，P=0.002）。②前瞻记忆任务正确率目标情绪效价的主效应有统计学意义（F=7.575，P=0.001），反应时的目标情绪效价主效应有统计学意义（F=3.196，P=0.044）；简单效应分析结果显示，抑郁组在负性条件下的反应时短于正性条件，正确率高于正性条件和中性条件（P<0.05或0.01）。③前瞻记忆任务正确率目标凸显性的主效应有统计学意义（F=6.659，P=0.012），凸显目标的正确率高于非凸显目标；反应时的主效应有统计学意义（F=10.106，P=0.002），凸显目标的反应时短于非凸显目标。结论 抑郁障碍患者对前瞻记忆任务中的负性目标表现出优先注意和优先加工；提高目标凸显性可能有助于促进抑郁障碍患者对前瞻记忆任务的自动化加工。 |
| 英文摘要: |
| Background Many studies have shown that patients with depressive disorder show impairments in prospective memory， while it is deemed necessary for facilitating their social reintegration， and the current research findings are inconsistent regarding the factors affecting prospective memory of patients with depressive disorder.Objective To explore the impact of target characteristics （emotional valence and salience） on prospective memory in patients with depressive disorder， so as to provide references for the training and recovery of prospective memory function in these patients.Methods From January to December 2022， 53 patients with depressive disorder were recruited from the outpatient department of Inner Mongolia Autonomous Mental Health Center. Meanwhile， 45 healthy individuals were concurrently recruited from surrounding communities as control group. An experiment with a 2 （participant type： depressive disorder， healthy control） ×2 （target salience： salient， non-salient） ×3 （emotional valence： positive， neutral， negative） factorial design was conducted. The positive/neutral/negative emotional pictures from Chinese Affective Picture System （CAPS） were used for emotional stimulation. A dual-task experimental paradigm was adopted， and the response time and accuracy in prospective memory task and ongoing task were recorded for participants with different target characteristics.Results ①In the prospective memory task， the main effect of participant type was statistically significant， with the depressive group showing lower accuracy （F=14.892， P<0.01） and longer response time （F=10.642， P=0.002） compared with control group. ② The main effect of target emotional valence on accuracy （F=7.575， P=0.001） and response time （F=3.196， P=0.044） in the prospective memory task was statistically significant. Simple effect analysis revealed that depressive group yielded a shorter response time and higher accuracy rate under negative conditions compared with positive and neutral conditions （P<0.05 or 0.01）. ③ The main effect of target salience on accuracy （F=6.659， P=0.012） and response time （F=10.106， P=0.002） in the prospective memory task was also statistically significant， with higher accuracy and shorter response time for salient targets compared with non-salient targets.Conclusion Patients with depressive disorder demonstrate preferential attention to and processing of negative stimuli in prospective memory tasks， while increasing target salience may facilitate spontaneous processing of prospective memory task in patients with depressive disorder. ［Funded by Inner Mongolia Health Commission Medical Health Science and Technology Project （number， 202202104）］ |
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