| HE Xiao - hua,ZHONG Yuan - hui,TAN Zhi -jian,LI Kang - quan,Efficacy on cognitive dysfunction in schizophrenia in risperidone and cerebroprotein hydrolysate treatment[J].SICHUAN MENTAL HEALTH,2014,27(1):55-56 |
| Efficacy on cognitive dysfunction in schizophrenia in risperidone and cerebroprotein hydrolysate treatment |
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| English keywords:Risperidone Cerebroprotein hydrolysate Schizophrenia Cognitive dysfunction |
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| English abstract: |
| Objective To investigate the clinical effects of risperidone combined cerebroprotein hydrolysate treated cognitive dys- function in schizophrenia. Methods 90 schizophrenia patients were randomly divided into the study group and the control group, and each group includes 45 patients. The control group were treated with risperidone , the study group 4 given risperidone combined cere- broprotein hydrolysate treatment , all treatment lasted for eight weeks. Both 2 groups were assessed with Wisconsin Card Sorting Test （WCST） , Wechsler Intelligence Scale（WAIS） and Wechsler Memory Scale（WMS）. Results On the baseline, there were no differ- ence between two groups in WCST, WMS and WAIS （ P 〉 0.05 ）. After 8 weeks treatment, both two groups performing better in WCST, WMS and WAIS, and the study group doing even better（P 〈0.05）. Adverse reactions of study group was 11.0 % while in the control group was 17.7%, which showed no significant difference （ P 〉 0.05 ）. Conclusion Risperidone combined cerebroprotein hydrolysate could effectively improve cognitive function and keep safe of schizophrenia patients |
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