| PAN Neng - rong,LI Ze,HUANG Zhi - yong,The study of treatment response of one week washout with MECT and subsequent treatment on treatment refractory depression[J].SICHUAN MENTAL HEALTH,2014,27(2):154-156 |
| The study of treatment response of one week washout with MECT and subsequent treatment on treatment refractory depression |
DOI：10.11886/scjsws201402018 |
| English keywords:Modified Electraconvulsive therapy Toyota Racing Development Washout |
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| Objective To evaluate the treatment response of a week washout with MECT and subsequent treatment on treatment refractory depression. Methods 40 patients with treatment refractory depression were discontinued all psychotropic drugs except henzodiazepines and received MECT for a week and subsequent antidepressant drugs combined with MECT treatment for five weeks. The HAMD - 17 ,HAMAand TESS were measured respectively before MECT and after MECT for 1,2,4,6 weeks. Results①After 6 weeks MECT, The symptoms of 14 patients were in remission, 17 patients had treatment response , and the efficiency rate is 77.5%. ②HAMD - 17 and HAMA scores were decreased significantly after a week treatment. There were significant differences in HAMD - 17 and HAMA scores afterl, 4, 6 weeks treatment compared with the baseline, at the same time, the scores at the end of 4 and 6 weeks treatment were significantly decreased than that at the end of 1 week treatment. Conclusion The effect of treatment withdrawal with MECT is good, and subsequent antidepressant drugs combined with MECT treatment can improve the therapeutic efficacy of the antidepressant drugs |
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