| ,Correlation between clinical features of obstructive sleep apnea patients and their anxiety and depression symptoms[J].SICHUAN MENTAL HEALTH,2019,32(1):33-37 |
| Correlation between clinical features of obstructive sleep apnea patients and their anxiety and depression symptoms |
DOI：10.11886/j.issn.1007-3256.2019.01.006 |
| English keywords:Obstructive sleep apnea Clinical features Anxiety Depression |
| Fund projects:四川省医学科研课题项目（S170400) |
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| Objective To explore the clinical characteristics of patients with obstructive sleep apnea ( OSA) and their relationship with anxiety and depression symptoms, and to provide references for further study on the specific mechanisms of occurrence among them. Methods A total of 238 patients who got polysomnography at the Sleep Medicine Center of Sichuan Mental Health Center from March 2018 to September 2018 were enrolled. They were divided into the OSA group ( n = 130) and the non - OSA group ( n = 108) according to the apnea hypopnea index ( AHI) . Clinical symptoms and sleep quality were assessed by self - made general information and clinical symptom questionnaire, the Epworth Sleeping Scale ( ESS) and Pittsburgh Sleep Quality Index ( PSQI) . The anxiety and depression condition were assessed by the Hamilton Anxiety Scale ( HAMA) and Hamilton Depression Scale - 24 item( HAMD - 24) . The correlation between clinical symptoms and anxiety and depression of the OSA group were analyzed. Results In the OSA group, snoring ( 76. 9% ) , suppress awake at night ( 25. 4% ) and cognitive impairment ( 76. 9% ) were more common than those in the non - OSA group ( 41 . 7% , 13. 0% , 63. 9% ) , and the duration were longer ( P < 0. 05 or 0. 01 ) . ESS, HAMA and HAMD - 24 scores of the OSA group were significantly higher than those of the non - OSA group ( P < 0. 01 ) . Correlation analysis showed that the duration of clinical symptoms in the OSA group was positively correlated with HAMA score ( r = 0. 212, P = 0. 016) . PSQI score was positively correlated with HAMA and HAMD - 24 scores ( r = 0. 217, 0. 211 , P = 0. 014, 0. 017) . Conclusion Patients with OSA often accompanied with snoring, suppress awake at night and cognitive impairment. The duration of symptoms were only related to the anxiety level, and the sleep quality were related to both anxiety and depression condition. |
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