| ,Efficacy of drug therapy combined with music therapy on curative effect and sleep quality of adolescents with first - episode depression[J].SICHUAN MENTAL HEALTH,2019,32(1):42-46 |
| Efficacy of drug therapy combined with music therapy on curative effect and sleep quality of adolescents with first - episode depression |
DOI：10.11886/j.issn.1007-3256.2019.01.008 |
| English keywords:First - episode depression Drug therapy Music therapy Polysomnography |
| Fund projects:乌鲁木齐市科学技术项目（Y141310045) |
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| Objective To observe the efficacy of drug combined with music therapy on the curative effect and sleep quality of patients with first - episode depression in adolescents, and to provide references for the selection of treatment plan for the patients. Methods From February 2016 to June 2017, a total of 98 adolescent patients who met the diagnostic criteria of Chinese Classification and Diagnostic Criteria of Mental Disease, third edition ( CCMD - 3) were selected from The Fourth People's Hospital of Urumqi. All subjects were divided into the observation group and control group by random number table method, and 49 cases in each group. Both groups were treated with sertraline hydrochloride ( 50 mg /d) and dexzopiclone ( 3 mg /d) , and the observation group received music therapy in addition. Both two groups were treated for 1 month. Hamilton Anxiety Scale ( HAMA) , Hamilton Depression Scale - 24 item ( HAMD - 24) , Pittsburgh Sleep Quality Index ( PSQI) and polysomnography ( PSG) were used to evaluate the two groups before and after treatment. Results After treatment, the total effective rate of the observation group was higher than that of the control group ( 93 . 88% vs. 79. 59% , χ2 = 4. 346, P < 0. 05 ) . After treatment, the HAMA and HAMD - 24 scores of the observation group were lower than those of the control group ( P < 0. 01 ) . All the factors scores of PSQI and the measured values of PSG of the observation group were better than those of the control group ( P < 0. 01 ) . Conclusion The combination of the drug and music therapy may help reduce anxiety and depression in adolescents with first - episode depression and improve their sleep quality. |
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