,Anti - ulcer effect of antidepressants in gastric ulcer model[J].SICHUAN MENTAL HEALTH,2019,32(2):185-189
Anti - ulcer effect of antidepressants in gastric ulcer model
DOI:10.11886/j.issn.1007-3256.2019.02.022
English keywords:Peptic ulcer  Antidepressants  Anti - ulcer effect
Fund projects:贵州省科技厅联合基金(黔科合LH字[2014]7109)
Author NameAffiliation
宋江兰 贵州医科大学精神病学教研室 
王雅静 贵州医科大学精神病学教研室 
朱祥路 贵州医科大学精神病学教研室 
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English abstract:
      With the progress of social civilization and the acceleration of the pace of life, disease related psychological factors and social factors attracted more and more attention. The medical model changed from the " biomedical model" to the " biological -psychological - social model" . Peptic ulcer is a typical psychosomatic disease closely related to anxiety and depression. The prevalence of peptic ulcer was rising and had become a significant public health concern. Recent studies showed that antidepressants can produce anti - ulcer activity in different ulcer models. This article reviewed the anti - ulcer mechanism of antidepressants and attempted to provide a more sufficient theoretical basis of peptic ulcer treatment.
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