,Anti - ulcer effect of antidepressants in gastric ulcer model[J].SICHUAN MENTAL HEALTH,2019,32(2):185-189 |
Anti - ulcer effect of antidepressants in gastric ulcer model |
DOI:10.11886/j.issn.1007-3256.2019.02.022 |
English keywords:Peptic ulcer Antidepressants Anti - ulcer effect |
Fund projects:贵州省科技厅联合基金(黔科合LH字[2014]7109) |
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English abstract: |
With the progress of social civilization and the acceleration of the pace of life, disease related psychological factors and social factors attracted more and more attention. The medical model changed from the " biomedical model" to the " biological -psychological - social model" . Peptic ulcer is a typical psychosomatic disease closely related to anxiety and depression. The prevalence of peptic ulcer was rising and had become a significant public health concern. Recent studies showed that antidepressants can produce anti - ulcer activity in different ulcer models. This article reviewed the anti - ulcer mechanism of antidepressants and attempted to provide a more sufficient theoretical basis of peptic ulcer treatment. |
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