| ,Research progress of gut-brain axis in schizophrenia[J].SICHUAN MENTAL HEALTH,2019,32(4):363-366 |
| Research progress of gut-brain axis in schizophrenia |
DOI：10.11886/j.issn.1007-3256.2019.04.017 |
| English keywords:Schizophrenia Gut-brainaxis Microbiotas Glutamate Dopamine Therapy resistance |
| Fund projects:北京市卫生系统高层次卫生技术人才培养计划(2015-3-111) |
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| The purpose of this article is to discuss the relationship between intestinal microorganisms, gut-brain axis and schizophrenia, and to inspire new ideas on the treatment of schizophrenia.The pathogenesis of schizophrenia still remains obscure,meanwhile, the hypotheses and studies have found that the onset and treatment response of schizophrenia are related to pathogenic microorganisms, especially the intestinal-brain axis of the human nervous system.The intestinal microbiota affects the mood,
behavior,and mental state of the host by releasing and secreting functional neurotransmitters that affect the levels of neurotransmitters associated with the central nervous system.This article reviews recent advances in microbiology, gut-brain axis and schizophrenia,and discusses the relationship between gut bacteria and host. |
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