Wang Queliang,Xie Zhibing,Liang Meiling,Cai Hualing,Gao Zhan,Efficacy and life satisfaction of sertraline hydrochloride combined with narrative psychotherapy for patients with depression disorder[J].SICHUAN MENTAL HEALTH,2019,32(6):506-509

Efficacy and life satisfaction of sertraline hydrochloride combined with narrative psychotherapy for patients with depression disorder

DOI：10.11886/scjsws20190427001

English keywords:Narrative psychotherapy Depression Satisfaction of life

Fund projects:珠海市科技计划项目 2014D0401990025 珠海市科技计划项目（2014D0401990025）

Author Name	Affiliation
Wang Queliang	Zhuhai Center for Chronic Disease Control, Zhuhai　 519000, China
Xie Zhibing	Zhuhai Center for Chronic Disease Control, Zhuhai　 519000, China
Liang Meiling	Zhuhai Center for Chronic Disease Control, Zhuhai　 519000, China
Cai Hualing	Zhuhai Center for Chronic Disease Control, Zhuhai　 519000, China
Gao Zhan	Zhuhai Center for Chronic Disease Control, Zhuhai　 519000, China

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English abstract:

Objective To explore the efficacy and life satisfaction of sertraline hydrochloride combined with narrative psychotherapy for patients with depression disorder. Methods From July 2015 to June 2018, a total of 64 outpatients and inpatients with depression disorder in Zhuhai Center for Chronic Disease Control who met the diagnostic criteria of International Classification of Diseases, tenth edition (ICD-10) were selected, and were randomly divided into the research group (n=32) and the control group (n=32) by random number table method. The research group was treated with sertraline hydrochloride tablets combined with narrative psychotherapy, while the control group was simply given sertraline hydrochloride tablets. Both groups were treated for 16 weeks. The efficacy was evaluated by the Hamilton Depression Scale-24 item (HAMD-24), and the satisfaction of life was assessed by the Life Satisfaction Index A (LSIA) before treatment and at the 2^nd, 4^th, 8^th, 12^th, 16^th weeks of the treatment. Results The HAMD-24 total scores of different treatment periods showed statistically significant difference within groups (F=439.462, P<0.01). The difference of HAMD-24 total score between the two groups was also statistically significant (F=7.035, P<0.05). There were interactions between different treatment times and treatment methods (F=4.791, P<0.01). The LSIA scores of different treatment periods showed statistically significant difference within groups (F=260.555, P<0.05). The difference of LSIA scores between the two groups was also statistically significant (F=26.750, P<0.05). There were interactions between different treatment times and treatment methods (F=14.841, P<0.05). There was no significant difference in adverse reactions between the two groups (χ ² =0.231, P>0.05). Conclusion Compared with sertraline hydrochloride alone, the combination with narrative psychotherapy has more obvious effect in improving the efficacy and life satisfaction of patients with depression disorder.

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