| Jiang Wenjuan,Hu Ke,Zhang Tongtong,Xu Qingting,Zhu Wei,Wang Guoqiang,Zhou Deyi,Efficacy of Chinese version of NoSAS score in screening obstructive sleep apnea syndrome in Han major depressive disorder patients[J].SICHUAN MENTAL HEALTH,2020,33(2):138-141 |
| Efficacy of Chinese version of NoSAS score in screening obstructive sleep apnea syndrome in Han major depressive disorder patients |
DOI：10.11886/scjsws20191029002 |
| English keywords:Depressive disorder Obstructive sleep apnea syndrome NoSAS score Polysomnography |
| Fund projects:无锡市科技发展项目（项目名称：ATS所致精神障碍疾病诊断标记物的开发和临床应用，项目编号：CSE31N1723）；无锡市卫生计生科研面上项目（项目名称：R-氯胺酮快速抗抑郁机制及应用研究，项目编号：MS201704） |
| Author Name | Affiliation | Postcode | | Jiang Wenjuan | The Third People’s Hospital of Jiangyin, Jiangyin 214400, China | 214400 | | Hu Ke | Wuxi Mental Health Center, Wuxi 214151, China
Graduate School of Wannan Medical College, Wuhu 241002, China | 241002 | | Zhang Tongtong | Wuxi Mental Health Center, Wuxi 214151, China
Graduate School of Wannan Medical College, Wuhu 241002, China | 241002 | | Xu Qingting | Wuxi Mental Health Center, Wuxi 214151, China | 214151 | | Zhu Wei | Wuxi Mental Health Center, Wuxi 214151, China | 214151 | | Wang Guoqiang | Wuxi Mental Health Center, Wuxi 214151, China | 214151 | | Zhou Deyi | Wuxi Mental Health Center, Wuxi 214151, China | 214151 |
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| English abstract: |
| Objective To evaluate the efficacy of Chinese version of NoSAS score in screening obstructive sleep apnea syndrome (OSAS) in Han Chinese patients with depressive disorder, so as to provide references for clinical screening of OSAS in patients with depressive disorder of the Han nationality.Methods Retrospective analysis was performed on the clinical data of patients with depression disorder who underwent polysomnography (PSG) monitoring in Wuxi Mental Health Center. The data of neck circumference, BMI, snoring history, age and sex were recorded. The diagnostic value of NoSAS score on OSAS was analyzed by ROC. The sensitivity, specificity, misdiagnosis rate, missed diagnosis rate and other data of NoSAS score were calculated in the form of four tables to judge the screening value.Results With AHI≥5 times/h as the cut-off point, 258 patients with depressive disorder were divided into OSAS group and non-OSAS group. There were statistically significant differences in age, gender, BMI, neck circumference, waist circumference, NoSAS score and AHI between the two groups (P<0.01). When AHI≥5 times/h was taken as the cut-off point, the area under the ROC curve of OSAS predicted by NoSAS score was 0.82 (P<0.01). When the AHI≥5 times/h and the NoSAS score > 8 was the cut-off point, the sensitivity of NoSAS was 59.32%, the specificity was 83.42%, the misdiagnosis rate was 18.09% and the missed diagnosis rate was 40.68%.Conclusion The Chinese version of NoSAS score has a better predictive effect on screening OSAS in Han Chinese patients with depressive disorder. |
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