| Tong Hao,Su Han,Kuang Xiaohong,Liao Dan,Zhang Xiaoyan,Yang Xin,Dai Minghui,Chen Yuanyuan,Che Lei,Du Chenying,Liu Chunxiu,Effect of mindfulness-based stress reduction combined with traditional chemotherapy on the quality of life of patients with myeloma bone disease[J].SICHUAN MENTAL HEALTH,2020,33(2):156-159 |
| Effect of mindfulness-based stress reduction combined with traditional chemotherapy on the quality of life of patients with myeloma bone disease |
DOI：10.11886/scjsws20200306001 |
| English keywords:Myeloma bone disease Mindfulness-based stress reduction Quality of life |
| Fund projects: |
| Author Name | Affiliation | Postcode | | Tong Hao | Sichuan Mental Health Center·The Third Hospital of Mianyang, Mianyang 621000, China | 621000 | | Su Han | Sichuan Mental Health Center·The Third Hospital of Mianyang, Mianyang 621000, China | 621000 | | Kuang Xiaohong | Sichuan Mental Health Center·The Third Hospital of Mianyang, Mianyang 621000, China | 621000 | | Liao Dan | Sichuan Mental Health Center·The Third Hospital of Mianyang, Mianyang 621000, China | 621000 | | Zhang Xiaoyan | Sichuan Mental Health Center·The Third Hospital of Mianyang, Mianyang 621000, China | 621000 | | Yang Xin | Sichuan Mental Health Center·The Third Hospital of Mianyang, Mianyang 621000, China | 621000 | | Dai Minghui | Sichuan Mental Health Center·The Third Hospital of Mianyang, Mianyang 621000, China | 621000 | | Chen Yuanyuan | Sichuan Mental Health Center·The Third Hospital of Mianyang, Mianyang 621000, China | 621000 | | Che Lei | Sichuan Mental Health Center·The Third Hospital of Mianyang, Mianyang 621000, China | 621000 | | Du Chenying | Sichuan Mental Health Center·The Third Hospital of Mianyang, Mianyang 621000, China | 621000 | | Liu Chunxiu | Sichuan Mental Health Center·The Third Hospital of Mianyang, Mianyang 621000, China | 621000 |
|
| Hits: |
| Download times: |
| English abstract: |
| Objective To explore the effect of mindfulness-based stress reduction combined with chemotherapy on improving the quality of life and remission rate of patients with myeloma bone disease, so as to provide references for improving the quality of life and treatment compliance of patients.Methods A total of 84 patients with myeloma bone disease who were hospitalized in the hematology department of The Third Hospital of Mianyang from January 2018 to January 2020 were selected as the research objects, and they were divided into the study group (n=42) and control group (n=42) by random number table method. Both groups were treated with BDT (bortezomib + dexamethasone + thalidomide) chemotherapy for 3 to 5 cycles. Based on this, the study group received mindfulness-based stress reduction therapy for 8 weeks. Before the treatment, 3 months and 6 months after intervention, the quality of life was assessed with Karnofsky Performance Status score (KPS), the pain level was assessed with Numerical Rating Scale (NRS), and the efficacy was assessed according to the international working group standard for efficacy of myeloma (IMWG).Results At the 6th month after intervention, the difference of life quality improvement rate between the study group and the control group was statistically significant (61.90% vs. 33.33%, χ2=6.65, P<0.05). At the 3rd and 6th month after intervention, NRS scores of the study group were lower than those of the control group, with statistically significant differences (P<0.05). However, there was no statistically significant difference in the degree of disease remission between the two groups (P>0.05).Conclusion Mindfulness-based stress reduction combined with traditional chemotherapy may improve the quality of life of patients with myeloma bone disease as well as better alleviate bone pain compared with conventional chemotherapy alone. |
| View Full Text
View/Add Comment Download reader |
| Close |
|
|
|