| Zhang Jiuping,Cheng Xin,Zhang Huihui,Xu Ping,Jin Peiying,Ke Xiaoyan,Distribution characteristics and medication analysis of mental diseases among 2153 children and adolescents hospitalized in psychiatry department[J].SICHUAN MENTAL HEALTH,2020,33(5):440-445 |
| Distribution characteristics and medication analysis of mental diseases among 2153 children and adolescents hospitalized in psychiatry department |
DOI：10.11886/scjsws20200810002 |
| English keywords:Children and adolescents Mental disease Hospitalization Medication |
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| Objective To investigate the distribution characteristics and medication of mental diseases among 2 153 children and adolescents hospitalized in Child Mental Health Research Center of Nanjing Brain Hospital.Methods A retrospective analysis was conducted on children and adolescents who discharged from Child Mental health Research Center of Nanjing Brain Hospital from March 2012 to July 2019， including the disease types， therapeutic drug types， drug doses， and etc.Results ① A total of 2 153 patients were included， and the most common diseases were schizophrenia and schizophrenia spectrum disorders （40.8%）， neurodevelopmental disorders and associated disorders （17.4%）， and depressive disorders （16.6%）. ② Of the selected patients， 2 098 patients （98.3%） had psychotropic drugs in their prescriptions， and the top five most commonly used psychotropic drugs were aripiprazole 677 cases （32.3%）， sertraline 570 cases （27.2%）， olanzapine 407 cases （19.4%）， risperidone 352 cases （16.8%） and sodium valproate 256 cases （12.2%）. ③ 2012-2019 annual comparative analysis showed that the frequency of antipsychotics used in the past three years was lower than that in the previous four years （P<0.05）， and no statistically significant difference was found in other drugs （P>0.05）. ④ Aripiprazole and risperidone were used more frequently in children group than those in adolescent group （P<0.05）， and the usage frequency of olanzapine， paliperidone and quetiapine in adolescent group was higher than those in children group （P<0.05）. Compared with female children， male children had a higher usage frequency of risperidone （P<0.05） and a lower usage frequency of aripiprazole and quetiapine （P<0.05）.Conclusion The medication of hospitalized children and adolescents with mental diseases changes over time， and the types of prescription drugs are closely related to the disease type， age， gender and times. |
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