| Wang Xian,Xu Weiyun,Xiong Jinxia,Shi Bohai,Li Chuan,Wang Zuowei,Effect of WeChat intervention on medication compliance， psychotic symptoms and recurrence rate of schizophrenic patients in community： a Meta-analysis[J].SICHUAN MENTAL HEALTH,2021,34(1):58-63 |
| Effect of WeChat intervention on medication compliance， psychotic symptoms and recurrence rate of schizophrenic patients in community： a Meta-analysis |
DOI：10.11886/scjsws20201108001 |
| English keywords:WeChat Schizophrenia Compliance Psychotic symptoms Recurrence rate Meta-analysis |
| Fund projects:国家重点研发计划（项目名称：基于移动医疗平台的抑郁障碍综合防治模式研发与应用，项目编号：2016YFC1307105）；上海市医学重点专科建设计划（项目名称：心境障碍科，项目编号：ZK2019A06）；上海市科学技术委员会科研计划项目（项目名称：上海市精神心理疾病临床医学研究中心，项目编号：19MC1911100）；虹口区卫生健康委员会科研课题计划资助（项目名称：基于微信平台的家属健康教育对精神分裂症患者服药依从性和疗效的影响，项目编号：虹卫1902-20） |
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| Objective To systematically review the efficacy of intervention by WeChat on medication compliance， psychotic symptom and recurrence rate of schizophrenic patients in community.Methods Databases including PubMed， the Cochrane Library， CBM， CNKI， Wanfang Data and VIP were searched electronically from January 1， 2011 to November 1， 2020 to collect randomized controlled trials （RCTs） about the effects of WeChat intervention on community schizophrenic patients. After two reviewers independently screened literature， extracted data and assessed the risk of bias of included studies， the meta-analysis was performed with Stata 12.0 software.Results A total of 381 articles were retrieved and finally 10 RCTs were included， including 1 251 patients with WeChat intervention group 641 cases and routine health education group 610 cases. Meta-analysis showed that compared with the conventional health education group， the WeChat intervention group had higher medication compliance （OR=3.05，95% CI：1.98~4.69，P<0.01）， lower PANSS score （SMD=-1.05，95% CI：-1.46~-0.64，P<0.01） and relapse rate （OR=0.34，95% CI：0.24~0.48，P<0.01）.Conclusion The interactive intervention based on WeChat platform can effectively improve the medication compliance of patients with schizophrenia in the community， help to reduce the severity of psychotic symptoms and the recurrence rate. |
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