Yue Lei,Zhu Xiumei,He Shijing,Yan Shaojing,Analysis of pathogenic bacteria of urinary tract infection in patients with mental disorders of different genders[J].SICHUAN MENTAL HEALTH,2022,35(3):245-249
Analysis of pathogenic bacteria of urinary tract infection in patients with mental disorders of different genders
DOI:10.11886/scjsws20211116002
English keywords:Psychiatry department  Urinary tract infection  Antibiotic  Drug resistance
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Author NameAffiliationPostcode
Yue Lei* Affiliated Brain Hospital of Guangzhou Medical University Guangzhou 510370 China 510370
Zhu Xiumei Affiliated Brain Hospital of Guangzhou Medical University Guangzhou 510370 China 510370
He Shijing Affiliated Brain Hospital of Guangzhou Medical University Guangzhou 510370 China 510370
Yan Shaojing Affiliated Brain Hospital of Guangzhou Medical University Guangzhou 510370 China 510370
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      Objective To analyze the gender differences in the pathogen distribution and drug susceptibility of bacteria causing urinary tract infection among psychiatric inpatients in a hospital in Guangzhou, and to provide a basis for clinical diagnosis and rational use of drugs in treatment.Methods Clinical data of 326 psychiatric patients complicating urinary tract infection in a hospital in Guangzhou from 2019 to 2020 were retrospectively analyzed, including 126 males and 200 females. Data including gender, age, identification results of urinary tract pathogens from urine samples and drug susceptibility results were collected. The differences in bacterial distribution and drug resistance rate of urinary tract infection pathogens in patients of different genders were analyzed.Results A total of 326 strains of urinary tract infection bacteria were isolated, including 103 strains (31.60%) of multi-drug resistant bacteria. Male and female urinary tract infection in patients with multi-drug resistant bacteria were detected 52 strains (41.27%) and 51 strains (25.50%), the detection rate of multi-drug resistant bacteria in female patients was significantly higher than that in male patients, with statistical difference (χ2=8.895, P<0.01). In terms of bacterial distribution, the composition ratio of Escherichia coli in female patients was higher than that in male patients (χ2=14.794), while the composition ratio of Acinetobacter baumannii and Pseudomonas aeruginosa was lower than that in male patients (χ2=13.665, 4.054), with statistical difference (P<0.05 or 0.01). The drug susceptibility results showed that Escherichia coli isolated from female patients were less resistant to various antibiotics such as ampicillin/sulbactam, aztreonam, cefepime, ceftazidime, levofloxacin, imipenem and meropenem than those from male patients (χ2=5.028~17.680, P<0.05 or 0.01).Conclusion The prevalence rate and bacterial distribution of psychiatric patients complicating urinary tract infection differ between patients of different genders, furthermore, the rate of drug resistance for Escherichia coli is lower in female patients than that in male patients.
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