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| 中国老年人抑郁障碍患病率Meta分析 |
| Prevalence of Major Depressive Disorder among Older Adults in China: A Meta-analysis. |
| 投稿时间：2024-03-30 修订日期：2024-11-15 |
| DOI： |
| 中文关键词: 抑郁症 患病率 老年人 Meta分析 |
| 英文关键词:Major depressive disorder Prevalence Elderly Meta-analysis |
| 基金项目:基金项目：浙江省卫生高层次人才工程，杭州市医药卫生科技项目（项目名称：红外线全身热疗在抑郁障碍治疗有效性和安全性的随机双盲安慰剂平行对照临床试验研究，项目编号：20201203B192） |
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| 中文摘要: |
| 背景 抑郁障碍是危害老年健康的常见精神疾病，了解其患病率对于推进健康老龄化意义重大。目的 对中国老年人抑郁障碍患病率进行Meta分析。方法 两名研究人员分别在中国知网、万方数据知识服务平台、维普网、中国生物医学文献数据库、PubMed、Springer、Web of science、Embase检索，获取中国老年人抑郁障碍患病率的原始文献，检索时间从各数据库建库至2022年12月。采用R软件进行Meta分析。结果 共纳入29篇文献，样本量共计63412人，抑郁障碍患病人数2341人。中国老年人抑郁障碍患病率为3.90%（95%CI 3.00%-4.90%）。亚组分析显示，无配偶的老年人抑郁障碍患病率为6.00%（95%CI 4.00%-9.00%）明显高于有配偶者患病率3.00%（95%CI 2.00%-4.00%）（p＜0.01）。女性抑郁障碍患病率为5.00%（95%CI 4.00%-6.00%）高于男性患病率4.00%（95%CI 2.00%-6.00%），农村抑郁障碍患病率为4.00%（95%CI 2.00%-8.00%）高于城市抑郁障碍患病率3.00%（95%CI 2.00%-4.00%），但差异均无统计学意义（p＞0.05）。初中以下及初中以上两组老年人抑郁障碍患病率差异无统计学意义（p＞0.05）。结论 中国老年人抑郁障碍患病率较高，需关注中国老年人情绪问题并积极预防干预，以改善晚年生活质量。 |
| 英文摘要: |
| Background Major depressive disorder (MDD) is one of the common disorders that deteriorates health in the elderly. It is significant to understand the prevalence of depression among the elderly to promote healthy aging. Objective To conduct a Meta-analysis on the prevalence of MDD among the elderly in China. Methods Two researchers independently searched CNKI, WanFang, CQVIP, SinoMed, PubMed, Springer, Web of Science and Embase databases to obtain the original literature on the prevalence of depression in Chinese older adults. Searches were conducted from database inception to December 2022. R software was used to analyze data. Results A total of 29 studies were included. The sample size was 63412, and 2341 participants were diagnosed with MDD. The prevalence of MDD in Chinese older adults was 3.90% (95% CI 3.00%-4.90%). The subgroup analysis showed that the prevalence of MDD in Chinese older adults without a spouse was 6.00% (95% CI 4.00%-9.00%), significantly higher than the 3.00% prevalence (95% CI 2.00%-4.00%) in those with a spouse (p<0.01). The prevalence of MDD in females was reported at 5.00% (95% CI 4.00%-6.00%), exceeding the male prevalence of 4.00% (95% CI 2.00%-6.00%), and the rural prevalence at 4.00% (95% CI 2.00%-8.00%) was higher than the urban rate of 3.00% (95% CI 2.00%-4.00%); however, these differences were not statistically significant (p>0.05). There was no significant difference in the prevalence of MDD between older adults with less than a junior high school education and those with at least a junior high school education. Conclusion There is a high prevalence of depression among the elderly in China. It is necessary to pay attention to the emotional problems of the elderly in China, and actively prevent and intervene to improve the quality of life in old age. |
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