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| 改良电休克治疗超高龄难治性抑郁症1例 |
| Ultra-elderly treatment resistant depression patient treated with modified electroconvulsive therapy: a case report |
| 投稿时间：2024-08-23 修订日期：2025-01-21 |
| DOI： |
| 中文关键词: 电休克 超高龄 难治性抑郁症 维持治疗 |
| 英文关键词:electroconvulsive therapy, ultra-elderly old patient, drug-refractory depression, maintenance treatment |
| 基金项目:国家重点研发计划（课题编号： 2019YFC0118502） |
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| 中文摘要: |
| 本文报道超高龄难治性抑郁症患者接受改良电休克治疗（MECT）1例。患者女性，87岁，抑郁症病史8年，间断发作性病程，既往对多种抗抑郁药物反应不佳，接受MECT后抑郁缓解。近2年患者经历生活应激事件后抑郁复发，接受MECT可好转，然而停止MECT后抑郁多次复燃，故在入院继续给予MECT以延续获益，患者对于MECT整体耐受性尚可。结合国内外研究文献，本文对超高龄难治性抑郁症患者的治疗选择进行探讨，以期为MECT在超高龄抑郁症患者中的应用提供参考。 |
| 英文摘要: |
| This article reports one case of a treatment resistant, ultra-elderly depressed patient who underwent modified electroconvulsive therapy (MECT). Patient was female, 87 years old, with a history of depression for 8 years, an intermittent episodic course, and had previously responded poorly to a variety of antidepressant medications, and her depression resolved after receiving electroconvulsive therapy. In the last 2 years, the patient experienced a recurrence of depression after a life event, and received MECT for improvement; however, the depression relapsed multiple times if discontinuing MECT. Therefore, in this instance of hospitalization, continuous MECT was given to continue the benefits, and the patient's overall tolerance for multiple electroconvulsive therapy sessions was good. In conjunction with a review of the literature, treatment options for super-elderly medically refractory depressed patients are discussed, providing a reference for the use of MECT in the treatment of ultra-elderly drug-refractory depression. |
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